A Case of Cryptococcosis Caused by <i>Cryptococcus gattii</i> in a Captive Queensland Koala（<i>Phascolarctos cinereus adustus</i>）

Abstract

We report the case of cryptococcosis caused by Cryptococcus gattii in a Queensland koala(Phascolarctos cinereus adustus) that died despite receiving an oral treatment of itraconazole and an inhalation of amphotericin B. Although the lesion caused by C. gattii was localized in the maxilla, a lateral nasal swelling and a pustular mass in the muzzle were also observed. Pseudomonas aeruginosa and Klebsiella pneumoniae infections were diagnosed in the liver, lungs, urogenital sinus, vertebral canal, and psoas. Immunosuppression by the koala retrovirus(KoRV) was suggested to be associated with the mixed infection because the koala tested positive for KoRV.