A Case of Cobalt Cardiomyopathy

Bonilla, Hilda Mariana Gonzalez; Bhimaraj, Arvind

doi:10.1016/s0735-1097(18)32927-9

Cited by 2 publications

(1 citation statement)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Definitive treatment of cobalt CM is ceasing exposure to cobalt. In the setting of implant related causes, treatment is by surgical removal of prosthesis [136].…”

Section: Heavy Metalsmentioning

confidence: 99%

Toxin-induced cardiomyopathy: A review and pooled analysis of pathophysiology, diagnosis and clinical management

Albakri¹

2019

Res Rev Insights

View full text Add to dashboard Cite

Research on drug-induced cardiomyopathy (CM) has largely focused on medically prescribed drugs due to reduced drug efficacy and complicated patient management. Investigation on other aetiologies -environmental toxins including cardiodepressant agents (ethanol), cardiostimulant agents (cocaine and amphetamine), heavy metals (cobalt, lead, mercury, arsenic, lithium or beryllium) and carbonaceous compounds (carbon monoxide or tetrachloride) have been relatively rarely. However, accumulating clinical data demonstrates that exposure to these environmental toxins has a pathogenic role mostly in populations with extreme dietary deficiency and/or long-term occupational exposure. Animal models of CM used to explore cardiotoxicity of environmental toxins have also heightened the awareness of their potential contributions to the pathogenesis of CM in the absence of any other known cause. Thus, the purpose of this paper is to review published evidence on toxic (non-medical drug) induced CM including a meta-analysis of causative toxins, pathophysiology, diagnosis and clinical management.

show abstract

“…Definitive treatment of cobalt CM is ceasing exposure to cobalt. In the setting of implant related causes, treatment is by surgical removal of prosthesis [136].…”

Section: Heavy Metalsmentioning

confidence: 99%