A Case of Ciprofloxacin-induced Acute Psychosis After Aortic Dissection Surgery

Abstract

Ciprofloxacin is widely used in general infected population, including patients with aortic dissection. Ciprofloxacin-mediated neurotoxicity has been observed in few reports, and some studies found ciprofloxacin may increase the incidence of aortic dissection or aortic aneurysm rupture. We report here a case of ciprofloxacin-induced acute psychosis after Sun’s total arch replacement and cardiopulmonary resuscitation. Based on the published literature and FDA hypothesis, we suggest that ciprofloxacin should be used cautiously in patients after aortic dissection surgery in the risk of drug-induced psychosis and residual dilated aortic rupture.