A Case of Carcinoma of the Cervix with a Blood Picture Simulating Chronic Aleukemic Eosinophilic Leukemia

Sala, Angelo M.; Stein, Robert J.

doi:10.1158/ajc.1937.125

Cited by 14 publications

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“…In all but one case the tumours with marked tissue eosinophilia were large cell nonkeratinising squamous carcinomas, which was the Accepted for publication 22 April 1981 most common histological variant in the whole series. No significant eosinophil infiltrate was seen in the endometrium or myometrium of these patients.…”

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confidence: 86%

Tumour-associated eosinophilia: a review.

Lowe¹,

Jorizzo²,

Hutt³

1981

J Clin Pathol

223

120

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During a recent study of 460 cases of cervical carcinoma from Malawi5 an assessment was made of cellular infiltration of the stroma within and adjacent to the tumour. In 13 cases (3 %) there was a very marked tissue eosinophilia with over 100 eosinophils per high power field of stroma. Eosinophils were seen both around and within the tumour, often separating the cells into small groups (Figs. 1-3). In some areas the tumour cells appeared to have lost cohesion, with individual cells lying separately encircled by eosinophils. The presence of eosinophils was not associated with tumour necrosis or with ulceration.The histological features of this group were characteristic, and appeared to be distinct from cases with minor degrees of tissue eosinophilia (37 % of the total), while in 60 % there were no eosinophils in the 10 fields examined. In all but one case the tumours with marked tissue eosinophilia were large cell nonkeratinising squamous carcinomas, which was the

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confidence: 86%