A Case of Benign Metastasizing Pulmonary Leiomyoma

Kang, Shin Ae; Choi, Sang In; Kim, Yeon A; Kim, Chong Ju; Yang, Donghwa; Kang, Jeong Han; Kie, Jeong Hae; Hong, Yong Kook; Lee, Sun Min

doi:10.4046/trd.2005.58.6.614

Cited by 6 publications

(12 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…We observed a patient with benign metastasizing leiomyomatosis, and to the best of our knowledge, this is the 4th reported case in Korea3-5). In this case, complete excision of the multiple nodules was performed.…”

Section: Discussionmentioning

confidence: 85%

Benign Pulmonary Metastasizing Leiomyomatosis: Case Report and a Review of the Literature

Kwon

Kim

Sohn

et al. 2006

Korean J Intern Med

View full text Add to dashboard Cite

The authors report here on a case of a nearly asymptomatic 51-year-old Korean woman who was found to have diffuse, multiple nodules of the lungs on a routine chest radiograph. She had undergone hysterectomy 16 years previously for uterine myoma. An open lung biopsy revealed tumor that was composed of interlacing bundles of spindle cells with cigar shaped nucleus and eosinophilic myofibrils in the cytoplasm; consistent with multiple leiomyomas. The stains for SMA, desmin, MSA and Ki-67 were positive and the stain for c-kit was negative. The other stains for estrogen and progesterone receptor were positive. During the open lung biopsy procedure, all the nodules were excised.We report here on an interesting case of benign metastasizing leiomyoma (BML) in 51-year-old patient. To the best of our knowledge, this case showed the longest period of clinical progression in Korea. This is also one of a few cases in which curative excision was successfully performed.

show abstract

Section: Discussionmentioning

confidence: 85%

Benign Pulmonary Metastasizing Leiomyomatosis: Case Report and a Review of the Literature

Kwon

Kim

Sohn

et al. 2006

Korean J Intern Med

View full text Add to dashboard Cite

show abstract

“…In one study, the mean duration between the hysterectomy and the appearance of the lung lesions was 15 years (range, 3 months to 20 years) [ 4 ]. To our knowledge, our case is the first report of metastatic lesion in the retroperitoneal cavity and lung occurring simultaneously in Korea, although 5 other cases of metastases to the lung alone after hysterectomy have been reported in Korea [ 5 - 9 ]. The term "BML" was used based on the presupposition that these tumors originate from the metastasis of the histologically benign-appearing uterine leiomyoma that cannot, based upon morphological criteria alone, be recognized as its malignant counterpart, leiomyosarcoma [ 1 ].…”

Section: Discussionmentioning

confidence: 99%

Pulmonary and retroperitoneal benign metastasizing leiomyoma

Lim

Park

Bae

et al. 2011

Clin Exp Reprod Med

View full text Add to dashboard Cite

Benign metastasizing leiomyoma (BML) is a rare disease, which usually occurs in women with a history of a prior hysterectomy or myomectomy for benign uterine leiomyoma, and has the potential to metastasize to distant sites, such as the lung, lymph nodes, muscular tissue, heart, or retroperitoneum. These lesions are slow-growing, asymptomatic, and usually found incidentally. The prognosis of BML is also excellent. However, there has been debate on the origin and the correct classification of BML, and there are no guidelines for the treatment of BML. We report here on a rare case of BML in both the retroperitoneal cavity and lung in a 48-year-old woman with a history of hysterectomy due to histologically benign uterine leiomyoma. The patient underwent retroperitoneal mass excision and bilateral salpingo-oophorectomy, and then wedge biopsy of two pulmonary nodules was performed additionally 9 days later. Until now, there has been no sign of recurrence and the patient remains asymptomatic. To our knowledge, pulmonary BML is rare and the co-existence of the retroperitoneal metastases after previous hysterectomy is even rarer.

show abstract

“…Both underwent a hysterectomy due to a benign uterine leiomyoma. After being diagnosed with abenign metastasizing leiomyoma, one was observed and the other was treated with a wedge resection of all the lung nodules 8,9 .…”

Section: Discussionmentioning

confidence: 99%

2 Cases of a Benign Pulmonary Metastasizing Leiomyoma

et al. 2009

View full text Add to dashboard Cite

A benign pulmonary metastasizing leiomyoma is a recognized clinical entity that has been infrequently reported in the medical literature. We report two cases of a benign pulmonary metastasizing leiomyoma. A 35-year-old woman who underwent myomectomy and a cesarean section approximately 6 years earlier visited our hospital for further evaluation of incidentally revealed multiple lung nodules. A diagnostic percutaneuous biopsy was performed. Finally she was diagnosed with a benign metastasizing leiomyoma. The patient then received LH-RH and has been followed up since. The other 44-year-old woman presented after an initial radiology evaluation revealed the presence of multiple, small-sized lung nodules. She underwent a right middle lung wedge resection to confirm the diagnosis. Finally she diagnosed with a benign metastasizing leiomyoma. The multiple lung nodules have been followed up closely.

show abstract

A Case of Benign Metastasizing Pulmonary Leiomyoma

Cited by 6 publications

References 4 publications

Benign Pulmonary Metastasizing Leiomyomatosis: Case Report and a Review of the Literature

Benign Pulmonary Metastasizing Leiomyomatosis: Case Report and a Review of the Literature

Pulmonary and retroperitoneal benign metastasizing leiomyoma

2 Cases of a Benign Pulmonary Metastasizing Leiomyoma

Contact Info

Product

Resources

About