Pulmonary and retroperitoneal benign metastasizing leiomyoma

Lim, Seung-Taik; Park, Joon Cheol; Bae, Jin‐Young; Kim, Jong In; Rhee, Jeong Ho

doi:10.5653/cerm.2011.38.3.174

Cited by 27 publications

(31 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…To our knowledge, there is only one other case report that describes the coexistence of retroperitoneal lymphogenic and pulmonary metastases of a benign leiomyoma 1. Next to that, according to our knowledge, BML has mostly been described after complete hysterectomy; one other case report describes a supracervical hysterectomy like this report 6.…”

Section: Discussionmentioning

confidence: 68%

See 1 more Smart Citation

Non-surgical intervention for retroperitoneal lymphogenic and pulmonary metastases of a benign leiomyoma: treatment with ulipristal acetate

Kortekaas

Pelikan²

2018

BMJ Case Reports

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 68%

“…They represent the extrauterine spread of multiple smooth muscle nodules frequently located in the lung, abdominal cavity, retroperitoneum, muscular tissue, lymph nodes, blood vessels or heart 1. The aetiology of these tumours remains controversial.…”

Section: Introductionmentioning

confidence: 99%

Non-surgical intervention for retroperitoneal lymphogenic and pulmonary metastases of a benign leiomyoma: treatment with ulipristal acetate

Kortekaas

Pelikan²

2018

BMJ Case Reports

View full text Add to dashboard Cite

“…BML has the potential to metastasize to distant sites such as the lung, lymph nodes, muscular tissue, heart, or retroperitoneum [2]. The underling pathogenesis of BML is not clearly understood.…”

Section: Discussionmentioning

confidence: 99%

A Woman with a Lung Mass and Multiple Pulmonary Nodules

Duncan

Kadaria

2015

Am J Case Rep

View full text Add to dashboard Cite

Patient: Female, 41Final Diagnosis: Benign metastatic leiomyomaSymptoms: Cough • shorthness of breathMedication: —Clinical Procedure: Bronchoscopy • open lung biopsySpecialty: PulmonologyObjective:Rare diseaseBackground:Patients presenting with lung mass and/or nodules are common problems for pulmonologists. The common etiologies for this condition in this area (Ohio River Mississippi Valley area) are malignancy, histoplasmosis, and sarcoidosis. However, there can be other rare causes of this presentation for which a detailed clinical history, examination, and broad knowledge is needed for diagnosis.Case Report:A 41-year-old woman presented with complaints of progressive nonproductive cough, shortness of breath, and decreased exercise limitation for several months. The symptoms were progressive and were hindering her daily work. Physical examination, including vital signs, was within normal limits. A chest X-ray followed by CT chest was done. CT chest showed a right infrahilar mass 3.5×2.5 cm along with multiple bilateral lung nodules of size 9 to 11 mm. Bronchoscopy with transbronchial needle aspiration (TBNA) and transbronchial biopsy (TBB) and CT-guided biopsy failed to show any diagnosis. Repeat CT scan at follow-up showed the same lesion and the patient had an open-lung biopsy. A diagnosis of benign metastasizing leiomyoma (BML) was made based on clinical, radiological, and histological features, and immunophenotype of the lesion. The patient was started on leuprolide (a GnRH agonist). Follow-up imaging showed decrease in size of lesions. The patient is asymptomatic with increased exercise tolerance.Conclusions:Clinicians need to be aware of rare causes of lung mass, like BML. This will help in timely diagnosis and treatment.

show abstract

“…BML can metastasize to distant organs, such as the lung, skin, bone, mediastinum, lymph nodes, muscular tissue, heart, and retroperitoneum [12]. Most patients with BML are diagnosed incidentally as they usually are symptoms-free [5].…”

Section: Discussionmentioning

confidence: 99%

Benign Metastasizing Leiomyoma: A Rare Type of Lung Metastases—Two Case Reports and Review of the Literature

Taftaf

Starnes

Wang

et al. 2014

Case Reports in Oncological Medicine

View full text Add to dashboard Cite

Benign metastasizing leiomyoma (BML) is a rare disease that usually occurs in women of reproductive age. They typically have history of uterine leiomyoma treated with hysterectomy. BML can metastasize to distant organs, with the lung being the most common organ. We report two patients who presented with benign metastasizing leiomyoma to the lung. Our first case was a fifty-two-year-old female who presented with multiple lung masses, with a past medical history of uterine leiomyoma who underwent hysterectomy 17 years ago. A CT-guided biopsy showed benign appearing spindle cells and pathology confirmed her diagnosis with additional positive estrogen/progesterone receptor stains. Our second case was a fifty-six-year-old female who presented with multiple cavitary pulmonary nodules. She subsequently underwent a video-assisted thoracoscopic surgery (VATS) with wedge resection of one of the nodules. Pathology confirmed the diagnosis based on morphology and immunohistochemical staining strongly positive for estrogen/progesterone receptors. Benign metastasizing leiomyoma is a rare condition which may affect women of reproductive age. This should be considered in the differential in patients who present with multiple pulmonary nodules, especially with a history of uterine leiomyoma. Additional stains, such as estrogen/progesterone receptors, may need to be done to confirm the diagnosis.

show abstract

Pulmonary and retroperitoneal benign metastasizing leiomyoma

Cited by 27 publications

References 12 publications

Non-surgical intervention for retroperitoneal lymphogenic and pulmonary metastases of a benign leiomyoma: treatment with ulipristal acetate

Non-surgical intervention for retroperitoneal lymphogenic and pulmonary metastases of a benign leiomyoma: treatment with ulipristal acetate

A Woman with a Lung Mass and Multiple Pulmonary Nodules

Benign Metastasizing Leiomyoma: A Rare Type of Lung Metastases—Two Case Reports and Review of the Literature

Contact Info

Product

Resources

About