A case of aquagenic syringeal acrokeratoderma with involvement of periungual area of the hand

Abstract

Gürel G, Şahin S, Çölgeçen E. A case of aquagenic syringeal acrokeratoderma with involvement of periungual area of the hand. Turk J Pediatr 2018; 60: 762-764.Aquagenic syringeal acrokeratoderma (ASA) is a rare form of palmoplantar keratoderma occurring after short-term contact with water. Although ASA usually involves the palmar region, there are also several cases with the involvement of dorsum of hand and sole of the feet. We described 15-year old girl who had white keratodermic plaques observed on the flexor side of distal phalanxes especially the periungual area after a 10 min contact with water. Our patient represents a rare case of ASA with the involvement of periungual region of the fingers.

Aquagenic keratoderma with dorsal involvement treated with botulinum toxin. Case report and review of literature

“…We objected the appearance of whitish cobblestone plaques in the palm and dorsal face of the fingers ( Figure 1A Aquagenic palmoplantar keratoderma is a rare acquired aberrant function of the sweat glands disorder in which patients develop skin thickening of palmar skin and the appearance of translucent papules after immersion in water. 1 Dorsal involvement of the hands, as shown in our case, is an unusual finding and only eight cases have been published (Table 1). [1][2][3][4][5][6][7][8] Among these patients, 44% 4 A remarkable but transitory resolution of the condition was achieved, as the patient relapsed after 2 months, although in a milder form than the outbreaks presented previously.…”

“…1 Dorsal involvement of the hands, as shown in our case, is an unusual finding and only eight cases have been published (Table 1). [1][2][3][4][5][6][7][8] Among these patients, 44% 4 A remarkable but transitory resolution of the condition was achieved, as the patient relapsed after 2 months, although in a milder form than the outbreaks presented previously. There are five other cases reported in the literature in which botulinum toxin is used, 9 although none of them describe dorsal involvement and higher doses were injected, between 50 and 100 IU.…”

Atypical familial aquagenic syringeal acrokeratoderma

“…Typical histologic findings of water‐exposed lesions in ASA include orthohyperkeratosis, dilated sweat duct ostia (which can be visualized with dermoscopy), 5,7,8,10,13 dilated eccrine ducts, hypergranulosis, acanthosis, hyperplasia of eccrine glands with clear‐cell change and vacuolation, and increased capillaries around eccrine coils 14 . We identified 134 cases of ASA reported in the literature and we summarize the commonly reported microscopic findings in Table 1 2‐11,14‐91 …”