A case of aortic dissection in a cocaine abuser: a case report and review of literature

Nusair, Maen; Abuzetun, Jamil Y.; Khaja, Azamuddin; Dohrmann, Mary L.

doi:10.1186/1757-1626-1-369

Cited by 12 publications

(10 citation statements)

References 8 publications

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“…It has been postulated that recurrent cocaine exposure makes the endothelium more permeable to atherogenic low density lipoprotein and may accelerate the migration of leukocytes to the aortic wall. Thus, predisposition to aortic dissection could include not only the impact of hypertension but chronic cocaine's effects on the aorta as well [38]. Clinical manifestations of aortic dissection may occur within minutes after cocaine exposure or up to 24 hours later [39].…”

Section: Discussionmentioning

confidence: 99%

Aortic dissection in cocaine abuse: A fatal case

D’Errico

Niballi

Bonuccelli

2018

Journal of Forensic and Legal Medicine

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Section: Discussionmentioning

confidence: 99%

Aortic dissection in cocaine abuse: A fatal case

D’Errico

Niballi

Bonuccelli

2018

Journal of Forensic and Legal Medicine

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“…[2][3][4] Symptoms may occur due to organ compression by an expanding haematoma (e.g dyspnea by tracheal or bronchus compression, dyshagia by esophageal compression or hoarseness by laryngeal nerve compression). 5 Painless AAD has been also reported. 6,7 There are three major classification system for aortic dissection depending on it's location and extent of aortic involvement.…”

Section: Introductionmentioning

confidence: 94%

A Case of Complicated Acute Type B Aortic Dissection

Chowdhury

Ghafoor

Salauddin

et al. 2015

Anwer Khan Mod Med Coll J

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A 60-years old hypertensive lady was referred to our hospital with suspected acute coronary syndrome with the complaints of shortness of breath for one day and abdominal pain for 2 days. Pain started at upper abdomen and lower chest, intense and sharp in nature radiated to lower abdomen and back. Initially she was admitted in a hospital as acute abdomen (Acute pancreatitis). Next day she developed respiratory distress and referred to our hospital. On examination her blood pressure was 180/100 mmHg and pulse 88 beat per minute. She had epigastric tenderness and on auscultation of lungs bilateral basal crepitation with rhonchi .Remainder of physical examination was unremarkable. Lab results showed mild anaemia, other results including amylase, lipase and cardiac markers were within normal limit. ECG showed T inversion in precordial and inferior leads. Her echocardiogram revealed absence of regional wall motion abnormality with good LV systolic function but there was mild pericardial and left sided plural effusion with suspected dissection of descending thoracic aorta from origin of IntroductionAcute aortic dissection (AAD) is a medical emergency which without appropriate treatment has 75% mortality within 2 weeks of the disease onset. 1 It usually presents with severe chest pain of sudden onset which without proper clinical evaluation and diagnostic imaging may be confused with acute myocardial infarction or pulmonary embolism and treated with drugs (Antithrombotic and anticoagulants) which are contraindicated in AAD. Some times pain may migrate to back if the dissection extends down the aorta. Less commonly the sign & symptoms are due to organ hypoperfusion and include peripheral ischemic syndromes, syncope, myocardial infarction or neurological symptoms. 2-4 Symptoms may occur due to organ compression by an expanding haematoma (e.g dyspnea by tracheal or bronchus compression, dyshagia by esophageal compression or hoarseness by laryngeal nerve compression). 5 Painless AAD has been also reported. 6,7 There are three major classification system for aortic dissection depending on it's location and extent of aortic involvement. These are (1) DeBakey types I, II and III; (2) Stanford types A and B and (3) The anatomical categories proximal and distal (Fig. 1). The basic principal of all these system of classification is for distinguishing aortic dissections with or without ascending aorta involvement as therapeutic approach and clinical outcome is determined by its involvement. Usually surgery is indicated if ascending aorta is A Case of Complicated Acute Type B Aortic Dissection

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“…Aortic dissection is one of the great imitators that can present in many ways clinically, depending on the portion of the aorta undergoing dissection. 1 Therefore, it is of utmost importance to discuss the variety of presentations, including those that are rare, so as not to miss this potentially fatal diagnosis. Our case is important because we believe that aortic dissection should warrant a high level of suspicion in a wide variety of patients, regardless of age, or medical or social history.…”

Section: Deadly Diarrhea: the Clever Disguise Of Aortic Dissectionmentioning

confidence: 99%