A Case of Amniotic Band Syndrome with Cleft Lip and Palate

Abstract

The patient was a 5-day-old boy born at 37 weeks and 4 days. At birth, an amniotic band encircling and constricting his left middle finger was noted, in addition to multiple anomalies including a right-side cleft lip and palate, a club foot, and syndactyly on the left hand. We performed cheiloplasty at 5 months, and palatoplasty at 18 months.

Sonographic Diagnosis of Thoracic Ectopia Cordis With Acrania

“…The more accepted is the extrinsic theory in which early amnion rupture leads to fibrous bands attaching to fetal parts, resulting in a range of abnormalities. [12][13][14] Depending on the region of attachment or constriction, webbing of the fingers or toes, limb amputations or defects (including clubfeet), craniofacial abnormalities, and visceral abnormalities may occur. 12,15 Treatment options for ectopia cordis most commonly require a multisurgical approach.…”

“…[12][13][14] Depending on the region of attachment or constriction, webbing of the fingers or toes, limb amputations or defects (including clubfeet), craniofacial abnormalities, and visceral abnormalities may occur. 12,15 Treatment options for ectopia cordis most commonly require a multisurgical approach. Repair of the omphalocele, sternal, diaphragmatic, and pericardial defects are included in the initial phase, followed by a soft tissue covering for the heart.…”

Management of the Amniotic Band Syndrome with Cleft Palate: Literature Review and Report of a Case

“…According to recent epidemiologic data, the occurrence of ABS is around 1 in 1,200–15,000 live births and it exhibits no special preference for a specific gender or race [ 4 ]; however, some studies report a slight preference for Afro-Caribbean individuals [ 2 ]. The pathogenesis of the ABS has not been totally elucidated, but it probably has a genetic origin.…”

“…Compression and adhesion of these amniotic bands, which float freely, may cause disruption of the fetal structures [ 7 ]. The fetus' arms and legs, tangled around the amniotic bands, may be amputated during intrauterine development due to loss of blood flow [ 4 , 8 , 9 ]. The variability in the type and severity of the anomalies caused by this syndrome can be attributed to the moment at which the amniotic membranes rupture.…”

A Case of Amniotic Band Sequence Complicated by Severe Skeletal Malocclusion

“…This syndrome is sporadic, reportedly occurring in approximately 1 in 12,000 -15,000 live births [3]. The clinical manifestations of ABS vary from death secondary to disruption of the umbilical cord or anencephaly, to amputations of extremities, facial cleft or lymphedema [4]- [7].…”