A Case of Acute Exudative Polymorphous Vitelliform Maculopathy: Follow-Up and Wide-Field Spectral-Domain Optical Coherence Tomography

Abstract

Acute exudative polymorphous vitelliform maculopathy is a disease that involves the outer retinal layers with lipofuscin deposits and serous detachment of the neuroepithelium with or without intraretinal cysts. Not much is known about the etiology and pathogenesis, and not many cases have been described. A review of the few clinical cases reported in the literature does not show a specific correspondence between etiology and SD-OCT findings.

Acute bilateral serous retinal detachments with spontaneous resolution in a 6-year-old boy

“…A few cases have been reported following a viral [ 5 ] or bacterial infection [ 6 ], [ 7 ], [ 8 ]. These cases were thought to be based on an autoimmune-mediated activation of inflammatory cells (presumably T lymphocytes as in Vogt-Koyanagi-Harada disease) at the level of the choroid, leading to profound choroidal swelling.…”

Idiopathic Acute Exudative Polymorphous Vitelliform Maculopathy: Insight into Imaging Features and Outcomes

“…Idiopathic exudative polymorphous vitelliform maculopathy (IEPVM) is a rare disease, described by Gass in 1988 [1]. Only 20 additional idiopathic cases have been reported, but several paraneoplastic or infection-related cases have been described [1][2][3][4]. Age at presentation varies, ranging from 13 to 69 years, and both genders are affected [2].…”

“…Only 20 additional idiopathic cases have been reported, but several paraneoplastic or infection-related cases have been described [1][2][3][4]. Age at presentation varies, ranging from 13 to 69 years, and both genders are affected [2]. This pathology is characterized by blurred vision, a mild decrease in visual acuity, and sometimes headaches [2].…”

“…Age at presentation varies, ranging from 13 to 69 years, and both genders are affected [2]. This pathology is characterized by blurred vision, a mild decrease in visual acuity, and sometimes headaches [2]. Patients present with multiple yellow-white, morphologically variable lesions at the level of the retinal pigment epithelium (RPE) and serous neurosensory detachments (SND) with polymorphous subretinal yellowish deposits [1].…”

“…Although a decrease in photoreceptor function usually persists over time, this disorder has a good visual prognosis, with visual acuity improvement as resolution of macular edema progresses [2,5].…”