A Case of a Schizophrenic Patient with Unusual Pharmacogenetics Profile

Abstract

There are plenty of evidences supporting the contribution of genetic variability to the mechanisms that responsible for both therapeutic and adverse effects of antipsychotic medications. We report a case that is an example of using cytochrome P450 pharmacogenetics and therapeutic drug monitoring in an attempt to guide schizophrenia treatment. This example illustrates the potential of applying the principles of predictive, preventive, and personalized medicine to the therapy of psychotic disorders.