A Brief Review of Swimming Endurance and Chronic Stress Model for Evaluation of Adaptogenic activity

Abstract

Stress is the disturbed homeostatic condition of the organism, and it is represented by non-specific response of the body to any demand imposed on it. Stress brings various changes in physiological condition of the organism, but various mechanism of the body will counteract to maintain homeostasis. In some situations, body’s adaptation to stress is like reward, which is responsible for improvement of body’s performance beyond its capacity. However if organism suffer strong acute or chronic stress, body is unable to maintain homeostasis. Under this condition, various types of diseases and disorders will develop, and even it may lead to death, if it is not managed at proper time. Hazardous stressful situation can be managed by using antistress agent or adaptogen. These agents improve physical and mental working capacity in severe stress circumstances. In different screening models for evaluation of adoptogenic activity, animals are challenged with acute or chronic stress conditions. Various stimulating, stress protective, tonic responses and biochemical markers were measured in evaluation of adoptogenic activity in these animal models.