A biocompatible polyurethane fluorescent emulsion with aggregation-induced emission for targeted tumor imaging

Abstract

The applications of fluorescence imaging in tumor detection and assistance in tumor resection have become progressively more widespread. Biocompatible fluorescent nanoparticles with high sensitivity and selectivity are challenge for biological...

Polyurethane Nanoparticles as Versatile Tools in Nanomedicine: A Review

“…Moreover, biocompatibility assessment tests both in vitro and in vivo showed that the fluorescent material has low toxicity and good biosafety. 108 provides an overview of the research results of PUNPs in imaging from 2019 to 2023. 4.3.…”

“…Ou et al 108 successfully prepared a biocompatible polyurethane fluorescent emulsion (PU-TPE-PBA (PTP)) by using PBA as a capping agent and TPE as a chain extender. These emulsion particles are long-lasting, small (48 nm), very sensitive, and stable at room temperature.…”

“…The findings showed that PTP with the targeting group had more cell fluorescence than PT without the targeting group. Moreover, biocompatibility assessment tests both in vitro and in vivo showed that the fluorescent material has low toxicity and good biosafety Table provides an overview of the research results of PUNPs in imaging from 2019 to 2023.…”

A biodegradable injectable fluorescent polyurethane-oxidized dextran hydrogel for non-invasive monitoring

“…TPE-NH 2 was synthesized as in our previous report. 48 Briefly, 0.3 mol zinc powder and 100 mL tetrahydrofuran were added to a three-necked flask in an ice-salt bath. After cooling down to −20 °C, TiCl 4 (0.15 mol) was added slowly and stirred.…”

Amphiphilic Polyurethane with Cluster-Induced Emission for Multichannel Bioimaging in Living Cell Systems

“…The global production of PU in 2021 was >23 million tons, with the global market value of >63 billion US dollars, making PU a rational alternative to traditional materials . Moreover, because of its excellent biological and blood compatibility, biodegradability, and wear- and aging-resistant properties, PU and its derivatives are widely used in biomedical fields such as tissue-engineering stents, surgical dressings/pressure-sensitive adhesives, antibacterial surfaces, and catheters. − At the same time, because of its good light stability, rich and diverse chemical composition and properties, PU derivatives have become popular new luminescent materials. − Therefore, the development of luminescent polyurethane materials is of great significance for theoretical research into NCLPs and their practical application in biomedicine.…”