A biocompatible bacterial cellulose/tannic acid composite with antibacterial and anti-biofilm activities for biomedical applications

Zhang, Zhaoyu; Sun, Yi; He, Wei; Yang, Yingying; Xie, Yu; Feng, Zhipeng; Qiao, Ke

doi:10.1016/j.msec.2019.110249

Cited by 117 publications

(67 citation statements)

References 61 publications

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“…In vitro release studies exhibited the improved release of tannic acid and desirable antibacterial activity against S. aureus, E. coli and P. aeruginosa . Thus the biomaterial can be applied as antibacterial wound dressing [104] .…”

Section: Biomaterials For Wound Managementmentioning

confidence: 99%

Recent trends on wound management: New therapeutic choices based on polymeric carriers

Okur

Karantas

Şenyiğit

et al. 2020

Asian Journal of Pharmaceutical Sciences

207

128

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Wound healing is an unmet therapeutic challenge among medical society since wound assessment and management is a complex procedure including several factors playing major role in healing process. Wounds can mainly be categorized as acute or chronic. It is well referred that the acute wound displays normal wound physiology while healing, in most cases, is seemed to progress through the normal phases of wound healing. On the other hand, a chronic wound is physiologically impaired. The main problem in wound management is that the majority of wounds are colonized with microbes, whereas this does not mean that all wounds will be infected. In this review, we address the problems that clinicians face to manage while treat acute and chronic wounds. Moreover, we demonstrate the pathophysiology, etiology, prognosis and microbiology of wounds. We further introduce the state of art in pharmaceutical technology field as part of wound management aiming to assist health professionals to overcome the current implications on wound assessment. In addition, authors review researches which included the use of gels and dermal films as wound healing agents. It can be said that natural and synthetic drugs or carriers provide promising solutions in order to meet the wound management standards. However, are the current strategies as desirable as medical society wish?

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Section: Biomaterials For Wound Managementmentioning

confidence: 99%

Recent trends on wound management: New therapeutic choices based on polymeric carriers

Okur

Karantas

Şenyiğit

et al. 2020

Asian Journal of Pharmaceutical Sciences

207

128

View full text Add to dashboard Cite

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“…Agarose-based hydrogels with tannic acid addition also show improved mechanical properties when compared to those without TA addition. Tannic acid has also been studied in combination with starch [129], silk fibroin [130], hyaluronic acid [131], and cellulose [132]. For all the complexes, an improvement in physicochemical and biological properties was noticed.…”

Section: Phenolic Acids With Other Natural Polymersmentioning

confidence: 99%

Collagen-Based Materials Modified by Phenolic Acids—A Review

Kaczmarek

Mazur

2020

Materials

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Collagen-based biomaterials constitute one of the most widely studied types of materials for biomedical applications. Low thermal and mechanical parameters are the main disadvantages of such structures. Moreover, they present low stability in the case of degradation by collagenase. To improve the properties of collagen-based materials, different types of cross-linkers have been researched. In recent years, phenolic acids have been studied as collagen modifiers. Mainly, tannic acid has been tested for collagen modification as it interacts with a polymeric chain by strong hydrogen bonds. When compared to pure collagen, such complexes show both antimicrobial activity and improved physicochemical properties. Less research reporting on other phenolic acids has been published. This review is a summary of the present knowledge about phenolic acids (e.g., tannic, ferulic, gallic, and caffeic acid) application as collagen cross-linkers. The studies concerning collagen-based materials with phenolic acids are summarized and discussed.

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“…The size of the inhibition zone of the drug-loaded stent against S. aureus and E. coli on the 12th day were 32.7 ± 1.3 and 31.7 ± 2.1 mm, respectively. Since BCG and WPU have no antibacterial properties, the size of the inhibition zone of the control group against S. aureus and E. coli on the 1st and 12th day was 0 [ 42 ].…”

Section: Resultsmentioning

confidence: 99%

Design and characterization of plasticized bacterial cellulose/waterborne polyurethane composite with antibacterial function for nasal stenting

Feng

Jin

et al. 2020

Regenerative Biomaterials

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A nasal stent capable of preventing adhesions and inflammation is of great value in treating nasal diseases. In order to solve the problems of tissue adhesion and inflammation response, we prepared plasticized bacterial cellulose (BCG) and waterborne polyurethane (WPU) composite with antibacterial function used as a novel nasal stent. The gelation behavior of BCG could contribute to protecting the paranasal sinus mucosa; meanwhile, the WPU with improved mechanical property was aimed at supporting the narrow nasal cavity. The thickness, size and the supporting force of the nasal stent could be adjusted according to the specific conditions of the nasal. Thermogravimetric analysis, contact angle and water absorption test were applied to investigate the thermal, hydrophilic and water absorption properties of the composite materials. The composite materials loaded with poly(hexamethylene biguanide) hydrochloride maintained well antibacterial activity over 12 days. Animal experiments further revealed that the mucosal epithelium mucosae damage of BCG−WPU composite was minor compared with that of WPU. This new type of drug-loaded nasal stent can effectively address the postoperative adhesions and infections while ensuring the health of nasal mucosal, and thus has an immense clinical application prospects in treating nasal diseases.

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A biocompatible bacterial cellulose/tannic acid composite with antibacterial and anti-biofilm activities for biomedical applications

Cited by 117 publications

References 61 publications

Recent trends on wound management: New therapeutic choices based on polymeric carriers

Recent trends on wound management: New therapeutic choices based on polymeric carriers

Collagen-Based Materials Modified by Phenolic Acids—A Review

Design and characterization of plasticized bacterial cellulose/waterborne polyurethane composite with antibacterial function for nasal stenting

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