A bioactive nanocomposite sponge for simultaneous hemostasis and antimicrobial therapy

Lei, Jiani; Li, Shanshan; Liu, Shuang; Wu, Qingyuan; Xu, Bolong; Huang, Zhijun; Wu, Nanping; Xiong, Xiaolu; Liu, Huiyu; Zhou, Dongsheng

doi:10.1007/s12274-022-5226-1

Cited by 6 publications

(8 citation statements)

References 33 publications

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“…There is a wide variety of nanocomposites formed by metal compound NPs with MSNs, and the available noble metal-free elements include 13 elements, such as calcium (Ca), 151,152 titanium (Ti), 153,154 vanadium (V), 155,156 manganese (Mn), 157,158 iron (Fe), 159,160 cobalt (Co), 161 copper (Cu), 162,163 zinc (Zn), 164,165 Niobium (Nb), 166,167 molybdenum (Mo), 168,169 cadmium (Cd), 51,170 iridium (Ir), 171 and bismuth (Bi) 172,173 (Fig. 4b).…”

Section: Metal Compound Nps/msns Nanocompositesmentioning

confidence: 99%

Multifunctional mesoporous silica nanoparticles for biomedical applications

Xu,

Li,

Shi

et al. 2023

Sig Transduct Target Ther

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Mesoporous silica nanoparticles (MSNs) are recognized as a prime example of nanotechnology applied in the biomedical field, due to their easily tunable structure and composition, diverse surface functionalization properties, and excellent biocompatibility. Over the past two decades, researchers have developed a wide variety of MSNs-based nanoplatforms through careful design and controlled preparation techniques, demonstrating their adaptability to various biomedical application scenarios. With the continuous breakthroughs of MSNs in the fields of biosensing, disease diagnosis and treatment, tissue engineering, etc., MSNs are gradually moving from basic research to clinical trials. In this review, we provide a detailed summary of MSNs in the biomedical field, beginning with a comprehensive overview of their development history. We then discuss the types of MSNs-based nanostructured architectures, as well as the classification of MSNs-based nanocomposites according to the elements existed in various inorganic functional components. Subsequently, we summarize the primary purposes of surface-functionalized modifications of MSNs. In the following, we discuss the biomedical applications of MSNs, and highlight the MSNs-based targeted therapeutic modalities currently developed. Given the importance of clinical translation, we also summarize the progress of MSNs in clinical trials. Finally, we take a perspective on the future direction and remaining challenges of MSNs in the biomedical field.

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Section: Metal Compound Nps/msns Nanocompositesmentioning

confidence: 99%

Multifunctional mesoporous silica nanoparticles for biomedical applications

Xu,

Li,

Shi

et al. 2023

Sig Transduct Target Ther

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“…40 Liu et al developed CaO 2 @SiO 2 /Chitosan as a calcium-based hemostatic agent that activates blood coagulation by releasing calcium. 41 Cuttlefish protects itself by a dark ink ejection against predators. 42 Cuttlefish ink (CFI) comprises naturally occurring nanoparticles with a diameter of 150 nm that contain mainly melanin, polysaccharides, and some proteins.…”

Section: Introductionmentioning

confidence: 99%

“…40 Liu et al developed CaO 2 @SiO 2 /Chitosan as a calcium-based hemostatic agent that activates blood coagulation by releasing calcium. 41…”

Section: Introductionmentioning

confidence: 99%

Development of an efficient hemostatic material based on cuttlefish ink nanoparticles loaded in cuttlebone biocomposite

Janahmadi,

Momeni,

Manoochehri

et al. 2024

J. Mater. Chem. B

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“…Previous studies have shown that Ca 2+ exerts a satisfactory coagulation effect in hemostatic materials. [28][29][30] This study represents the first attempt to use shells as a precursor, combined with tourmaline, to prepare hemostatic materials.…”

Section: Introductionmentioning

confidence: 99%