Abstract:A pico-ampere sensitive electrochemical sensor signal acquisition chain consisting of a multi-channel bidirectional current-mirror based potentiostat and a multiplexed current-input delta-sigma (AM) ADC is presented. Slice-based class-AB amplifiers with output stage current replication using reconfigurable current-mirrors enable bidirectional current sensing over a range of five decades. The replicated current is digitized by the ADC. The proposed circuit achieves a minimum detectable current of 91.7 pA, resul… Show more
“…Our proposed floating differential DAC is part of an integrated potentiostat [28] and manufactured in a 130 nm standard CMOS process. The DAC is designed for a supply voltage of 3 V, but can operate at supply voltages down to 2 V. Decreasing the supply voltage decreases the DACs output voltage range.…”
Section: Realizationmentioning
confidence: 99%
“…. Micrograph of the manufactured integrated potentiostat[28] with a layout overlay. The DAC and the positioning circuit are shown in more detail.…”
“…Our proposed floating differential DAC is part of an integrated potentiostat [28] and manufactured in a 130 nm standard CMOS process. The DAC is designed for a supply voltage of 3 V, but can operate at supply voltages down to 2 V. Decreasing the supply voltage decreases the DACs output voltage range.…”
Section: Realizationmentioning
confidence: 99%
“…. Micrograph of the manufactured integrated potentiostat[28] with a layout overlay. The DAC and the positioning circuit are shown in more detail.…”
“…Our proposed floating differential DAC is part of an grated potentiostat [28] and manufactured in a 130 nm standard process. The DAC is designed for a supply voltage of 3 V, but can operate at supply voltages down to 2 V. Decreasing the supply voltage decreases the DACs output voltage range.…”
“…The scaled sensor signal at the output of the preamplification stage is converted by a ∆Σ ADC. The ADC is an advanced version of the circuit proposed in [12]. A secondorder continuous-time loop filter topology with an inherent anti-aliasing property is used.…”
A fully differential potentiometric sensor interface consisting of a high input impedance programmable-gain preamplification stage followed by a delta-sigma (∆Σ) ADC is presented. The reconfigurable circuit achieves a dynamic range of 92 dB and a resolution of 126 µV, thus enabling electrochemical analyses for multiple biochemical parameters. The fully differential topology of the signal acquisition chain in combination with the use of feedforward compensated opamps leads to a high interference robustness of the implementation. Compared to a single-ended topology, PSRR, CMRR and EMIRR improvements by 43.3 dB, 6.8 dB and 21.6 dB, respectively, are achieved. These properties and the low power and area consumption of 75 µW and 0.081 mm 2 allow the circuit to be used in wirelessly powered electrochemical point-of-care (PoC) diagnostics.Index Terms-biosensor, delta-sigma (∆Σ) ADC, feedforward, frequency compensation, interference robustness, potentiometry, programmable-gain amplifier (PGA), wireless power transfer (WPT).
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