A benign ancient schwannoma of the tibia nerve

Madi, Sandesh; Pandey, Vivek; Mannava, Kirankumar; Acharya, Kiran

doi:10.1136/bcr-2016-215620

Cited by 7 publications

(10 citation statements)

References 4 publications

(2 reference statements)

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“…[9][10][11][12][13] On MRI, schwannomas typically appear spindle shaped, oval, round, or even cystic, and they reveal a homogeneous contrast enhancement. 4,14,15 Similar image characteristics can be observed in neurofibroma and even malignant PNSTs. 9,15 For this reason, Karsy et al emphasized the need for additional imaging modalities to achieve a better preoperative diagnostic workup.…”

Section: Introductionmentioning

confidence: 55%

Quantitative Analysis of Superb Microvascular Imaging versus Color-Coded Doppler Sonography for Preoperative Evaluation of Vascularization of Schwannomas

Kloth

Eissler

Schmidberger

et al. 2019

J Neurol Surg A Cent Eur Neurosurg

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Purpose Comparison of vascularization of schwannomas, benign peripheral nerve sheath tumors, using color-coded Doppler sonography (CCDS) and the Toshiba monochrome Superb Microvascular Imaging (mSMI) (Minato, Tokyo, Japan) technique. Methods In a retrospective single-center analysis, 16 patients were identified with histologically confirmed schwannomas. Between March and June 2018, all of them underwent ultrasonography using mSMI and CCDS before surgery. Schwannoma vascularization was quantitatively measured using ImageJ, an open platform for scientific image analysis. As the diagnostic gold standard, magnetic resonance imaging was mandatory. Results The mSMI and CCDS vascularization showed a moderate agreement between the techniques (κ = 0.5556; p = 0.0066). The quantitative visual assessment of the vascularization revealed no difference (25.3 ± 8.2 vs. 18.2 ± 3.8; p = 0.0532). Significant differences were found for the quantitative assessment of CCDS with ImageJ (26.8 ± 8.8 vs. 19.3 ± 2.8; p = 0.0368). However, in a subanalysis of highly vascularized schwannomas, mSMI revealed significant differences to slightly vascularized schwannomas (32.0 ± 8.2 vs. 21.3 ± 6.1; p = 0.0065) but not between moderately and slightly vascularized types (p = not significant). Conclusion The mSMI mode is qualitatively superior to conventional CCDS; however, quantitative analysis of the vascularization of schwannomas revealed no significant quantitative advantage for mSMI. Nevertheless, the mean ImageJ values showed a positive trend toward a better representation of the vascularization degree of schwannomas with mSMI.

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Section: Introductionmentioning

confidence: 55%

Quantitative Analysis of Superb Microvascular Imaging versus Color-Coded Doppler Sonography for Preoperative Evaluation of Vascularization of Schwannomas

Kloth

Eissler

Schmidberger

et al. 2019

J Neurol Surg A Cent Eur Neurosurg

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“…3,5,8 Schwannoma of the tibial nerve or sciatic nerve, for example, can mimic the radicular pain in the legs, which can lead to an erroneous diagnosis of radiculopathy. 11 Involvement of the brachial plexus is uncommon, and usually presents as a palpable, slow-growing, supraclavicular or axillary mass, usually without pain or neurological signs. 3 Predictors of malignancy include rapid tumor growth, positive predictive value (PPV) of 95%, and presence of any loss of neurologic function (PPVof 73%), which probably reflects nerve injury.…”

Section: Clinical Manifestationsmentioning

confidence: 99%

“…All of the imaging modalities presented here are useful in the preoperative diagnosis of schwannomas; however, each of these methods has limitations in distinguishing the different types of tumors from the nerve sheath and establishing a differentiation between benign and malignant lesions. 11 Although they do not have specificity, they are endowed with a certain diagnostic value, and some radiological characteristics can help doctors differentiate these tumors, helping to guide their approach. 13…”

Section: Diagnostic Imagingmentioning

confidence: 99%

“…On ultrasonography (US), most PNSTs, including schwannomas, are hypoechogenic and have posterior acoustic reinforcement, making them look like a ganglion cyst, which can also be observed in other tumors of uniform cellularity, such as lymphomas. 5,11,12 The presence of blood flow on the Doppler can distinguish a PNST from a cystic lesion. 5 On US, schwannomas appear as well-defined, ovoid, heterogeneous masses together with cystic degeneration and eccentric location.…”

Section: Ultrasonographymentioning

confidence: 99%

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Peripheral Nerve Schwannomas: A Literature Review

et al. 2019

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Introduction Schwannomas are benign tumors originating from the cells, which wrap around axons that are usually encapsulated and solitary. These tumors usually lead to little or no symptomatology. They are usually the most common peripheral nerve tumors in adults, with their highest incidence between the third and fifth decades of life. Objective To perform a review about schwannoma of the peripheral nerves, presenting its definition, epidemiology, diagnosis, symptomatology and treatment. Methodology This is a descriptive work, based on a review of articles available in the PubMed database with the descriptors schwannoma and peripheral nerves. Results and Discussion Only papers published between 1981 and 2019, describing studies in humans, and that were available as full articles were selected. A total of 391 articles were included; after reading the titles, we noted that 67 articles fit the topic of the present study. Among the articles selected for reading, 33 fit the objectives of the present work, and were considered for the writing of the present article. Conclusion Schwannomas are benign myelin sheath tumors that develop with local symptomatology or asymptomatic and present a good surgical prognosis with generally reduced rates of surgical complications.

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“…It is a benign nerve sheath tumor that originates from Schwann cells of the peripheral nerves and presents with various clinical symptoms. In most reported cases, excision resulted in the amelioration of symptoms . However, the persistence of pain, even after complete excision, causes clinicians to suspect nerve injury–induced neuropathic pain or other pathologies such as radiculopathy.…”

Section: Introductionmentioning

confidence: 99%