A ascorbic acid-imprinted poly(o-phenylenediamine)/zeolite imidazole frameworks-67/carbon cloth for electrochemical sensing ascorbic acid

A review of zeolitic imidazolate frameworks (ZIFs) as electrochemical sensors for important small biomolecules in human body fluids

“…The use of MIPs is extremely helpful in improving the selectivity and stability for the determination of AA. 132 A dual-signal strategy was established in the developed sensor, which includes an increase in current response of tyrosine and a decrease in poly thionine. This strategy utilizes π–π stacking interactions and hydrogen bonding to recognize tyrosine and efficiently reduce potential interferences from intrinsic background electrochemical signals, resulting in improved sensitivity and accuracy.…”

“…A complex AA-imprinted MIP sensor has been reported, which was synthesized firstly by growing ZIF-67 on carbon cloth (CC) to obtain ZIF-67/CC as a working electrode, and then AA-imprinted ploy(o-PD) was successively deposited through electropolymerization on the surface of ZIF-67/CC electrode. 132 At last, the AA-poly(o-PD)/ZIF-67CC was placed in a mixture of K Cl and ethanol to remove AA to obtain MIPs/ZIF-67/CC electrode. Moreover, the MIPs/ZIF-67/CC electrode exhibited superior performance to CC, ZIF-67/CC, and NIPs/ZIF-67/CC.…”

“…13 MIPs offer several advantages, such as specific recognition ability, good stability, low cost, ease of preparation, high selectivity, long service life, and wide application range. 85,132 Despite their advantages, MIPs also have some limitations, such as poor conductivity, a limited number of imprinted cavities, and low sensitivity. However, the integration of MIPs with suitable electrocatalytic nanomaterials can lead to the development of sensors with improved electrochemical performance, addressing these issues.…”

A Mini Overview of Biomedical Utilization of Zeolitic Imidazolate Frameworks

“…Moreover, silica@ZIF-8 can sense atropine [43] and bimetallic ZIF/carbon nanofibers (CoMnZIF-CNF) composite can sense adrenaline [44]. Ascorbic acid can be sensed using ZIF-8/Pt NPs/GCE sensor [45], AA-imprinted poly(o-PD)/ZIF-67/CC [46] and C-dots/ZIF-8/MnO2 [47]. ZIF-67 derivatives such as ZIF-67/AgNWs Nanocomposite have the ability to sense Folic Acid [48] and EDAPbCl4@ZIF-67 has the ability to detect protocatechuic acid [49].…”