A 48-month randomized controlled trial of caries prevention effect of a one-time application of glass ionomer sealant versus resin sealant

Abstract

The aim of this study was to compare the caries prevention effectiveness, retention rates and the level of fluoride of saliva of a glassionomer sealant (GIS) with that of a resin-based sealant (RS). Eighty GIS and 80RS were placed on the first permanent molars in 40 children aged 7-10 years. Children were re-examined at 6, 12, 24, 36 and 48 months after the procedure. Saliva samples were collected before the sealant was applied and again at each appointment, and fluoride levels were measured. After 48 months, occlusal caries were seen in 4 and 12 teeth in GIS and RS groups respectively. There was a statistically significant difference in the fluoride levels of saliva between baseline and up to 12th month in GIS group. GISs presented effective prevention of caries development, even though the failure rate is higher when compared to the RSs. An increased salivary fluoride level due to GISs might be an additive effect on the prevention of dental caries.

Evaluating the Retention of Resin-Based Sealant and a Glass Ionomer Sealant among 7-10 Year-Old Children: A Randomized Controlled Trial

“…In our study, school children aged between 7-10 years were selected. This was in accordance with the study by Winkler M, et al [8], Kumaran P, et al [9], and Haznedaroglu, et al [10]. Children and adults can benefit from sealants, but the earlier we get them, the better is the effect of sealants as the highest risk of occlusal caries is believed to exist during the eruption of teeth as well as after the first few years, not only because of mineral immaturity as post-eruptive maturation has not taken place but also due to the more intense dental plaque accrual because of infra-occlusion [11].…”

“…They found a statistical difference in the retention between the two sealants (p < 0.001). Haznedaroglu E, et al [10] compared resin sealant and GI sealant over a period of 4 years with recall interval at 6 th , 12 th , 24 th , 36 th , and 48 th month and a statistical difference was found between the resin and GI sealant (p = 0.005). In a study conducted by Chavez M, et al [16], the clinical condition of the materials (resin sealant and GI sealant) used were evaluated after three and six months.…”

The Use of Pit and Fissure Sealants—A Literature Review

“…Another recent clinical trial compared the effectiveness of caries prevention between GI sealants and RBS after 48 months and found four carious lesions in the GI group and 12 in the RBS group, but the difference was not statistically significant. The GI sealant was therefore shown to be an effective measure in caries prevention, although it had a significantly lower retention rate compared to RBS [ 43 ]. A possible reason behind the caries preventive effect of of GIC, despite it not being as retentive as RBS, is that GI remains in the deepest areas of the fissures, even though it is not clinically evident [ 44 ].…”

Imagistic Analysis of Dental Adhesives Loaded with Nanoparticles Used on Teeth Sealing of Pits and Fissures with Resin Based Materials

“…Among the advantages of glassionomer sealants is the change in fluoride level in the oral cavity, which can lead to an increased rate of caries prevention. Over time, compared to resins based sealants, glassionomer sealants had a higher failure rate [8].…”