A 20-year study of persistence of lower urinary tract symptoms and urinary incontinence in young women treated in childhood

Abstract

Objective: To determine whether urinary incontinence (UI) and lower urinary tract symptoms (LUTS) persist over years, patients treated for UI and LUTS in childhood were reevaluated in adulthood. Materials and methods: Forty-seven women (cases) treated in childhood for daytime UI/LUTS (group A) and nocturnal enuresis (group B) self-completed (average age: 24.89 AE 3.5 years) the International Consultation on Incontinence Questionnaire for Female with LUTS (ICIQ-FLUTS). ICIQ-FLUTS was self-administered to 111 healthy women (average age: 23 AE 5.1 years) from a nursing school as a control group. Data obtained from ICIQ-FLUTS and quality of life (QoL) score (0e10) were compared (Fisher's exact test) between patients and controls, and between group A (n Z 28) and group B (n Z 19). Results: Prevalence of LUTS was higher in patients than in controls. The difference between patients and controls was statistically significant (p Z 0.0001) for UI (34% vs. 7%) and feeling of incomplete bladder emptying (49% vs. 28%). QoL score was >5 in 59% of patients and 1% of controls (p Z 0.0001). No significant differences were found between groups A and B. Conclusions: UI and LUTS are confirmed in young women who suffered for the same condition in childhood. Longitudinal studies are needed to assess if these symptoms persist or are newly onset.

A Pilot Randomized Controlled Trial Evaluating the Effectiveness of Group vs Individual Urotherapy in Decreasing Symptoms Associated with Bladder-Bowel Dysfunction

“…8 Moreover, women with lower urinary tract symptoms have a higher prevalence of childhood BBD than their healthy counterparts. 18,19 Further longitudinal studies are warranted to explore the natural history of BBD and identify subgroups of higher risk patients who may have BBD that persists into adulthood. Since our followup was short (3 months), it was impossible to determine which group would Treatment Group Figure 2.…”

Re: Long-Term Followup of Children with Nocturnal Enuresis: Increased Frequency of Nocturia in Adulthood

“…6 We hope the results of our parallel group, randomized, controlled trial prompt other investigators to explore the effectiveness of these techniques against regional infiltration in a prospective systematic fashion.Lastly we wish to reemphasize the primary finding in our report, that surgeon provided local infiltration works quite well! We also directed the injection superiorly, as close to the costal margin as possible, to reach a high thoracic nerve level.…”

Long-term functional and psychosocial outcome in adolescents and young adults treated for lower urinary tract dysfunction in childhood

“…5-7 A higher number of urinary tract symptoms are reported in young women after treatment for childhood LUTD compared to healthy age-related controls. 8,9 Other authors found childhood LUTD to be an independent risk factor for urinary tract symptoms in adulthood. 6 Childhood LUTD is associated with lowered self-image, lower quality of life(QOL) and a negative impact on psychosocial wellbeing at the time of occurence.…”

“…Data about the number and types of urinary tract symptoms in adolescents and young adults treated for functional childhood LUTD is scarce since children are lost to follow-up by their paediatricians/ paediatric urologists upon reaching adulthood. Previous studies mainly include either middle-aged adults, in whom comorbidities might act as a confounder, or young females 5,8 . Less is known about the presence of urinary tract symptoms and QOL in, for example, young males or adolescents previously treated for LUTD.…”