A 10 second colorimetric test for asymptomatic bacteriuria in pregnancy

Slowinski, Eugene J.; Smith, Leon G.

doi:10.1016/0002-9378(66)90024-x

Cited by 6 publications

(4 citation statements)

References 13 publications

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“…The use of the filter paper-Griess test together with a culture method (either incorporated together or separately) should be helpful in screening programs and follow-up of patients. As shown in this and other studies (4, 6, 9, [18][19][20], when used with a first morning specimen which the patients can test or bring to the office, a positive Griess test strongly suggests the presence of urinary infection. The Griess test is clearly not useful for testing randomly collected specimens where the duration of incubation in the bladder is unknown.…”

Section: Discussionsupporting

confidence: 69%

“…In addition to bacteriological methods (2,3,5,7,8,(10)(11)(12), chemical screening tests have been devised based upon reduction of nitrate to nitrite (the Griess test) by bacteria (4,6,9,(18)(19)(20), removal of residual amounts of glucose in the urine by bacterial action (7,13,15), presence of enzymes in urine derived from bacteria or inflammatory cells such as catalase, and reduction of tetrazolium salts by bacteria after standardized incubation of voided urine (4,16). In general, most culture methods have the advantage of being both highly sensitive and specific, providing presumptive identification and permitting subculture to obtain antimicrobial susceptibility information.…”

mentioning

confidence: 99%

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Evaluation of New Urinary Tract Infection Screening Devices

Craig¹,

Kunin²,

DeGroot³

1973

Applied Microbiology

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Several new methods for detection of bacteriuria were studied to evaluate their usefulness as screening procedures. A new filter paper device incorporating dehydrated media and tetrazolium was found to be reliable when compared with the standard pour plate method in the laboratory and with the dip-slide method in a field test. It failed to detect yeasts and slowly growing streptococci. Antibiotics blocked the test when susceptible organisms were present. An agar-cup method was found to be quite reliable, but could be improved by use of differential media. The Griess test was confirmed in a small trial to be highly specific when used in conjunction with a firsf morning specimen, but of little value with random specimens. Phenzopyridine was found to give false positive reactions. The subnormal glucose test, although highly sensitive and specific, gave too many false positive tests to be useful other than as a screening method.

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Section: Discussionsupporting

confidence: 69%

mentioning

confidence: 99%

Evaluation of New Urinary Tract Infection Screening Devices

Craig¹,

Kunin²,

DeGroot³

1973

Applied Microbiology

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“…Several screening tests for significant bacteriuria have been proposed. 2 The Griess test is a colorimetric test for the presence of nitrites in the urine. Significant populations of pathogenic bacteria will convert ever-present nitrate to nitrites after a short incubation time in the bladder.…”

Section: Identification Of the Padeni At Riakmentioning

confidence: 99%

Screening for Bacteriuria in Pregnancy

Slowinski

1968

Postgraduate Medicine

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“…However, we have found that urine microscopy has a poor sensitivity and positive predictive value and also requires the services of a trained laboratory technician. The Griess test has been shown to have a sensitivity of 60 to 100% in detection of early pregnancy AB (3,4). It is a simple inexpensive test that can be carried out by unskilled personnel (4).…”

mentioning

confidence: 99%

The Griess Test: An Inexpensive Screening Test for Asymptomatic Bacteriuria in Pregnancy

Mathews

George

Mathews

et al. 1998

Aust NZ J Obst Gynaeco

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This study was designed to compare urine microscopy and the Griess test as screening tests for asymptomatic bacteriuria (AB) in pregnancy, using urine culture as a gold standard. Urine microscopy, Griess test and urine culture were carried out on urine samples from 483 antenatal women. AB was detected by urine culture in 30 (6.8%) of the patients. The Griess test and urine microscopy were found to have a sensitivity of 63.3% and 60%, specificity of 99.5% and 83.6%; and positive predictive value of 90.5% and 21.1% respectively. Most of the infections missed by the Griess test were either <100,000 colony count on culture or caused by gram positive cocci. The cost of the Griess test was only one tenth of that of urine microscopy. The Griess test is a simple and inexpensive test that when compared to urine microscopy has equal sensitivity, and better specificity and positive predictive value for the detection of AB in pregnancy than urine microscopy.

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A 10 second colorimetric test for asymptomatic bacteriuria in pregnancy

Cited by 6 publications

References 13 publications

Evaluation of New Urinary Tract Infection Screening Devices

Evaluation of New Urinary Tract Infection Screening Devices

Screening for Bacteriuria in Pregnancy

The Griess Test: An Inexpensive Screening Test for Asymptomatic Bacteriuria in Pregnancy

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