The application of superconducting circuits for high-performance computing and high-speed analog-to-digital converters suffers from the difficulty of amplifying the weak signals of superconducting circuits to the volt level of semiconductor electronics. We refer to the most accepted Josephson circuit used to amplify weak signals of about a millivolt to several tens of millivolts as a Suzuki stack. It can be directly triggered by a single flux quantum pulse and has a very high switching speed of about 25 ps.We report here an in-depth study of design issues for Suzuki stacks with extensive systematic simulations as well as experimental results. We explain the origin of previously reported phenomena such as multiple-level switching, high bit-error-rates, and interactions between stacks, and give design guidance for avoidance of such problems. We show experimental results for a set of Suzuki stacks operating correctly and independently with a single power supply.The presented design guidelines address important characteristics that need to be optimized: output voltage, bias margins, operating frequency, bit-error-rate, delay, power dissipation, and physical size.