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Abstract

* The study was conducted as part of a scientific program «Scientific justification for improving health care and public health quality», state registration number 0110U07572. Institution, which financed the research: Ministry of Health of Ukraine.

Chitosan-based multifunctional oxygenating antibiotic hydrogel dressings for managing chronic infection in diabetic wounds

“…19,21,48,49 Despite these observations there are other beneficial wound healing processes supplemental oxygenation for MACF could encourage as tied to oxidative cellular metabolic processes. 4,5,50…”

“…3 This challenge can be further exacerbated by diabetic angiopathy and ischemia, which limit oxygen and supply of nutrients to the site of injury, leading to inflammation and increased risk of infection. 4,5 Combating diabetic wound infections is often achieved via systemic and/or local antibiotic therapy to treat or prevent infections. 6…”