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Gültekin, Bahadır; Beyazpınar, Deniz Sarp; Ersoy, Özgür; Özkan, Murat; Akay, Tankut; Sezgin, Atilla

doi:10.6002/ect.tdtd2015.o15

Exp Clin Transplant

2015

DOI: 10.6002/ect.tdtd2015.o15

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Bahadır Gültekin

Deniz Sarp Beyazpınar²,

Özgür Ersoy³

et al.

Abstract: Objectives: Acute kidney injury is a frequent complication after orthotopic cardiac transplant. We aimed to describe the risk factors for acute kidney injury after cardiac transplant according to Kidney Disease: Improving Global Outcomes criteria. ; P = .033), and more frequently had a history of hypertension (P = .011) and smoking (P = .007) than did patients without acute kidney injury. They also had lower intraoperative urine output (453.380 ± 266.85 mL) than did patients who did not develop acute kidney in… Show more

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Cited by 2 publications

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Risk factors of renal replacement therapy after heart transplantation: a retrospective single-center study

Xie¹,

Fu²,

Wu³

et al. 2022

Ann Transl Med

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Background: Acute kidney injury (AKI) and renal replacement therapy (RRT) are common after heart transplantation (HT). The need for RRT has been reported to be one of the most important predictors of a poor prognosis after HT. Therefore, it is important to early identify risk factors of RRT after HT. However, in the heart transplantation setting, the risk factors are less well studied, and some of the conclusions are controversial. This study aimed to identify the clinical predictors of RRT after HT.Methods: This single-center, retrospective study from January 2010 to June 2021 analyzed risk factors (pre-, intra-, and postoperative characteristics) of 163 patients who underwent HT. The endpoint of the study was RRT within 7 days of HT. Risk factors were analyzed by multivariable logistic regression models.Results: Fifty-five (33.74%) recipients required RRT within 7 days of HT. Factors independently associated with RRT after HT were as follows: a baseline estimated glomerular filtration rate (eGFR) <60 mL/min per 1.73 m 2 [odds ratio (

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Risk factors of renal replacement therapy after heart transplantation: a retrospective single-center study

Xie¹,

Fu²,

Wu³

et al. 2022

Ann Transl Med

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Acute Kidney Injury in Patients Undergoing Cardiac Transplantation: A Meta-Analysis

et al. 2019

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Background: Acute kidney injury (AKI) is a common complication following solid-organ transplantation. However, the epidemiology of AKI and mortality risk of AKI among patients undergoing cardiac transplantation is not uniformly described. We conducted this study to assess the incidence of AKI and mortality risk of AKI in adult patients after cardiac transplantation. Methods: A systematic review of EMBASE, MEDLINE, and Cochrane Databases was performed until June 2019 to identify studies evaluating the incidence of AKI (by standard AKI definitions), AKI requiring renal replacement therapy (RRT), and mortality risk of AKI in patients undergoing cardiac transplantation. Pooled AKI incidence and mortality risk from the included studies were consolidated by random-effects model. The protocol for this study is registered with PROSPERO (no. CRD42019134577). Results: 27 cohort studies with 137,201 patients undergoing cardiac transplantation were identified. Pooled estimated incidence of AKI and AKI requiring RRT was 47.1% (95% CI: 37.6–56.7%) and 11.8% (95% CI: 7.2–18.8%), respectively. The pooled ORs of hospital mortality and/or 90-day mortality among patients undergoing cardiac transplantation with AKI and AKI requiring RRT were 3.46 (95% CI, 2.40–4.97) and 13.05 (95% CI, 6.89–24.70), respectively. The pooled ORs of 1-year mortality among patients with AKI and AKI requiring RRT were 2.26 (95% CI, 1.56–3.26) and 3.89 (95% CI, 2.49–6.08), respectively. Conclusion: Among patients undergoing cardiac transplantation, the incidence of AKI and severe AKI requiring RRT are 47.1% and 11.8%, respectively. AKI post cardiac transplantation is associated with reduced short term and 1-year patient survival.

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Untitled

Cited by 2 publications

References 8 publications

Risk factors of renal replacement therapy after heart transplantation: a retrospective single-center study

Risk factors of renal replacement therapy after heart transplantation: a retrospective single-center study

Acute Kidney Injury in Patients Undergoing Cardiac Transplantation: A Meta-Analysis

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