“…One method proposed for the determination of unknown moderately volatile organic impurities in liquid extracts of pharmaceutical preparations improves the selectivity of the determination and decreases the detection limit of impurities because of the use of a two-step open-tube chromatography in the off-line mode and preconcentration [175][176][177]. The method is applicable to the determination of impurities more and less volatile than the main component.…”
Data reported in the literature on methods for the determination of organic impurities in pharmaceutical preparations are systematized; the characteristics and possibilities of the methods are compared.
“…One method proposed for the determination of unknown moderately volatile organic impurities in liquid extracts of pharmaceutical preparations improves the selectivity of the determination and decreases the detection limit of impurities because of the use of a two-step open-tube chromatography in the off-line mode and preconcentration [175][176][177]. The method is applicable to the determination of impurities more and less volatile than the main component.…”
Data reported in the literature on methods for the determination of organic impurities in pharmaceutical preparations are systematized; the characteristics and possibilities of the methods are compared.
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