Pharmaceuticals and Related Drugs

Using of liquid chromatography coupled with diode array detector for determination of naphthoquinones in plants and for investigation of influence of pH of cultivation medium on content of plumbagin in Dionaea muscipula

“…The development of new analytical techniques used for a determination of biologically active compounds is one of the most important tasks of analytical chemistry, biochemistry and pharmacy [24,[27][28][29][30][31][32][33][34][35]. Here we wished to study the content of naphthoquinones (1,4-naphthoquinone, lawsone, juglone and plumbagin; Fig.…”

Prevalence and Detection of Counterfeit Pharmaceuticals: A Mini Review

“…Every instrumental pharmaceutical analysis technique , has, to some extent, potential for the detection and fingerprinting of counterfeit drugs. However, only the most recent reports found in the peer-reviewed literature, with special emphasis on those that have been effectively applied to the analysis of fake medicines, are described here.…”

Simultaneous Separation of Four Types of Steroid Hormones by Micellar Electrokinetic Chromatography with Cetyltrimethylammonium Bromide

“…Other analytical techniques for identification and quantification of steroids include gas chromatography-mass spectrometry, 8,9 supercritical fluid chromatography, 10,11 liquid column chromatography-mass spectrometry, 12,13 and thin-layer chromatography. 14,15 When compared to immunoassays, these separation techniques provide low matrix interferences, while their sensitivities are relatively lower.…”

“…Due to its high efficiency, low sample and solvent consumption, and rapidity, capillary electrophoresis (CE) has become one of the most powerful tools for the determination of steroids. 14,15 Among them, micellar electrokinetic chromatography (MEKC) based techniques using anionic micelles as pseudostationary phases provide the highest resolving power for the separation of steroids and related compounds, [16][17][18][19][20][21][22][23][24][25][26][27][28] for example, glycodeoxycholate micelles, 17 sodium dodecyl sulfate (SDS) micelles, [18][19][20][21] and sodium cholate micelles. [22][23][24] In addition, mixed micellar solutions consisting of sodium cholate and sodium deoxycholates, 25 SDS and sodium taurocholate, 1 SDS and g-cyclodextrin, 26 sodium taurodeoxycholate and g-cyclodextrin, 27 or SDS and sodium cholate have been tested.…”