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Amago, Samuel

doi:10.1023/a:1012947422263

Cited by 9 publications

(1 citation statement)

References 12 publications

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“…To verify the possible presence of non linearity in autoMEP data matrix, and consequently to improve the robustness of our model, we have decided to carry out a non linear QSAR method, such as the Response Surface Analysis (RSA), comparing the performances of both statistical methodologies [7][8][9]. RSA As regards adenosine receptor antagonists, including A 3 -selective compounds, an extensive literature is present [12][13]19].…”

Section: Introductionmentioning

confidence: 99%

Response Surface Analysis as Alternative 3D-QSAR Tool: Human A3 Adenosine Receptor Antagonists as a Key Study

Bacilieri¹,

Kaseda²,

Spalluto³

et al. 2007

LDDD

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3D-QSAR methodologies represent a useful, widespread tool in drug discovery and optimisation.Here we introduce an alternative QSAR tool for model generation: the non-linear Response Surface Analysis, that finds at present great application in Design of Experiment for optimizing drug production processes. Binding affinity estimation of human A 3 adenosine receptor antagonists is considered as key study.

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Section: Introductionmentioning

confidence: 99%

Response Surface Analysis as Alternative 3D-QSAR Tool: Human A3 Adenosine Receptor Antagonists as a Key Study

Bacilieri¹,

Kaseda²,

Spalluto³

et al. 2007

LDDD

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Topograf�a E Hipotiposis: Dos Tipos De ?Rebeld�a Descriptiva? Con Un prop�sito conjunto en nada De Carmen Laforet

Muñoz–Basols

2005

Neophilologus

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La vi salir hace un rato. Se veı´a mal. Llevaba una maleta. Le pregunte´cuando volverı´a y respondio´que nunca jama´s.'' (Final de La piel del cielo, Elena Poniatowska) AbstractThe hermeneutics of description in Nada (1945) enables the deciphering of the semantic inner structure of the novel. This is achieved by means of an intentional characterization of both space and characters. The narrative mechanism of description is constructed primarily along two dimensions: 'topography,' or a description of places, and 'hypotyposis,' a vivid description of objects and characters through the use of sensorial imagery. The presence of both types of description in the novel allows the reader to better comprehend the psychology of Andrea, the protagonist. At the same time, Carmen Laforet's use of detailed description provides a revealing and critical portrait of Spanish society under Franco's regime. While Andrea never exteriorizes any opposition to prevailing norms, we maintain that by means of the aforementioned rhetorical techniques, the novel represents a defiant response to the social archetypes of the period. For this reason, our reading of the novel lays claim to the relevance of the description process internalized with the reader. Neophilologus (2005) 89: 235-248 Ó Springer 2005

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Spanish Literature in the Long Twentieth Century, 1898–2007

Pérez-Sánchez

2014

The Cambridge History of Gay and Lesbian Literature

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Cited by 9 publications

References 12 publications

Response Surface Analysis as Alternative 3D-QSAR Tool: Human A3 Adenosine Receptor Antagonists as a Key Study

Response Surface Analysis as Alternative 3D-QSAR Tool: Human A3 Adenosine Receptor Antagonists as a Key Study

Topograf�a E Hipotiposis: Dos Tipos De ?Rebeld�a Descriptiva? Con Un prop�sito conjunto en nada De Carmen Laforet

Spanish Literature in the Long Twentieth Century, 1898–2007

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