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Abstract

The concentrations of C-reactive protein (CRP) and alpha1-acid glycoprotein (AAG) were evaluated in 1-, 3- and 18-month-old dogs (four of each age) that had been inoculated with turpentine oil. The CRP and AAG in 3-month-old and younger dogs subjected to surgery or inoculated with either Staphylococcus aureus or a viral vaccine were also evaluated. The average CRP concentration in the sera peaked 2 days after inoculation of turpentine oil. The peak CRP concentrations in 3- and 18-month-old dogs were significantly (p < 0.05) greater than those in 1-month-old dogs. The average AAG concentration in the sera peaked 4 days after inoculation of turpentine oil. No significant difference was found in AAG concentrations between any of the age groups. When experimentally inoculated with S. aureus or subjected to oophorohysterectomy, the CRP and AAG concentrations increased in 3-month-old dogs, but they increased little in 1-month-old dogs. The CRP and AAG in dogs inoculated with the viral vaccine did not increase. In dogs with fractures or subjected to percutaneous gastrostomy, the CRP and AAG concentrations correlated with the condition of dogs.

C-reactive protein, glucose and iron concentrations are significantly altered in dogs undergoing open ovariohysterectomy or ovariectomy

“…There was no difference between groups. OHE has previously been shown to cause moderately elevated CRP in dogs [ 16 , 26 ]; however, to a lesser degree than more invasive surgery like orthopedic surgery [ 26 ]. In a study of humans, a smaller elevation of CRP was detected after laparoscopic hysterectomy compared to the open abdominal procedure [ 38 ], and the same phenomenon has been identified in dogs [ 14 ].…”

Effects of subclinical inflammation on C-reactive protein and haptoglobin levels as well as specific humoral immunity in dogs vaccinated against canine distemper and parvovirus

“…The increases in CRP and Hp in group II and III are likely to be associated with their involvement in the regulation of inflammatory immune response and repair of inflammation-injured tissues [9, 13]. Normalisation of CRP concentrations in group II, which did not occur until the final two measurement points, reflects the gradual subsidence of inflammation.…”

“…Group I dogs were administered Nobivac® DHP, the vaccine against distemper, infectious hepatitis and parvovirus whereas group II animals received subcutaneous turpentine oil (1 ml/10 kg b.w.) [9] to induce subclinical inflammation, followed by Nobivac® DHP after 24 h. Animals in group III received only turpentine oil in the way and amount identical to that as in group II.…”

Orosomucoid, a New Biomarker in the Association between Obesity and Periodontitis

“…Neutrophils and monocytes can also synthesize orosomucoid and thus contribute to the elevation of this protein in the serum of patients with sepsis. Interestingly, C reactive protein is an acute phase inflammatory marker whereas orosomucoid is a chronic phase marker [33], [34]. The combined assessment of CRP and orosomucoid profiles can be used to diagnose, date and monitor the inflammatory syndrome: in an early onset reaction, only CRP increases; then both CRP and orosomucoid increase; and after a successful treatment, CRP decreases first.…”