96114755 Hormone replacement therapy and skin ageing

Vaillant, L.; Callens, Anne-Céline

doi:10.1016/0378-5122(96)81782-8

Cited by 5 publications

(4 citation statements)

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“…Aging is an inalterable process in which both extrinsic and intrinsic determinants induce a loss of structural integrity and physiological function . Extrinsic skin aging is caused by exogenous factors such as sun exposure, environmental toxins and infectious agents , whereas intrinsic skin aging is determined by genetic influences, age and internal factors such as hormones and metabolic substances . Histologically, the intrinsic aged skin shows a thinning of all layers, epidermal and dermal atrophy, increased heterogeneity in size of basal cells, flattening of the dermoepidermal junction, decreased vasculature, as well as reduced numbers of melanocytes, Langerhans cells and fibroblasts .…”

Section: Introductionmentioning

confidence: 74%

Comparative analysis of intrinsic skin aging between Caucasian and Asian subjects by slide‐free in vivo harmonic generation microscopy

Lin

Liao

Wei

et al. 2019

Journal of Biophotonics

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Phenotypical and functional differences in the intrinsic skin aging process of individuals between Caucasians and Asians have generated considerable interest in dermatology and cosmetic industry. Most of the studies focused on the stratum corneum, and in some other studies inter-individual differences overwhelms the racial difference. None of the studies comparatively analyzes the difference from the histopathological point of view. Here we report our harmonic generation microscopy study to analyze the difference of intrinsic aging between Caucasian and Asian skin from a histopathological point of view. As a result, the cellular and nuclear areas of basal cells in Caucasian subjects were found to increase at the same rate as the Asian subjects, ideal for scoring age. The maximum thickness of the viable epidermis, the dermal papilla (DP) volume per unit area and the depth of the DP zone in Caucasians were found to decrease at faster rates than those in Asians. K E Y W O R D SAsian, Caucasian, dermal papillae, harmonic generation microscopy, in vivo imaging, intrinsic aging, race, viable epidermis

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Section: Introductionmentioning

confidence: 74%

Comparative analysis of intrinsic skin aging between Caucasian and Asian subjects by slide‐free in vivo harmonic generation microscopy

Lin

Liao

Wei

et al. 2019

Journal of Biophotonics

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“…Aging is a consequence of genetic program and cumulative environmental damage, which contributes to a progressive loss of structural integrity and physiological tasks of the skin [2,3]. The intrinsic aging (physiological-, chronological-, UV-protected aging) of the skin is determined by genetic influences and internal factors such as hormones or metabolic substances [4]. Intrinsic aging is mainly controlled by progressive telomere shortening [5].…”

Section: Introductionmentioning

confidence: 99%

Skin Aging: A Brief Summary of Characteristic Changes

Raschke

Elsner

2010

Textbook of Aging Skin

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“…Skin aging is due to intrinsic (chronological) aging, photoaging (exposure to ultraviolet radiation), and hormonal aging (estrogen deficiency) (1). Skin aging manifests as atrophy of the extracellular matrix (ECM) and wrinkling, and delayed wound healing (2)(3)(4).…”

Section: Introductionmentioning

confidence: 99%

Beneficial regulation of type I collagen and matrixmetalloproteinase-1 expression by estrogen, progesterone, and its combination in skin fibroblasts.

Philips

Devaney

2003

AGE

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There is impaired wound healing and loss of type I collagen in skin aging, which can be improved by topical estrogen in vivo. The goal of this study was to determine the effects of estrogen, and progesterone and a combination of estrogen and progesterone as well, on the proliferation and the expression of type I collagen and matrixmetalloprotienase-1 (MMP-1, degrades collagen) in dermal fibroblasts (cells that synthesize collagen and MMP-1) in-vitro. Estrogen, progesterone, and its combination similarly and significantly inhibited cell proliferation and MMP-1 protein levels, and simultaneously stimulated type I collagen expression in the fibroblasts, indicating beneficial modulation.

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96114755 Hormone replacement therapy and skin ageing

Cited by 5 publications

References 0 publications

Comparative analysis of intrinsic skin aging between Caucasian and Asian subjects by slide‐free in vivo harmonic generation microscopy

Comparative analysis of intrinsic skin aging between Caucasian and Asian subjects by slide‐free in vivo harmonic generation microscopy

Skin Aging: A Brief Summary of Characteristic Changes

Beneficial regulation of type I collagen and matrixmetalloproteinase-1 expression by estrogen, progesterone, and its combination in skin fibroblasts.

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