8F-FDG whole body PET/CT dose evaluation in pediatric patients

Rossi, Luisa; Zito, Felicia; Galetta, G.; Florimonte, Luigia; Orunesu, Eva; Castellani, Massimo; Canzi, Cristina; Voltini, Franco; Benti, Riccardo

doi:10.1016/j.ejmp.2016.01.388

Cited by 1 publication

(1 citation statement)

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“…However, they all agreed that low-dose radiation exposure increases the lifetime probability of developing cancers and other radiation-induced diseases [18]. Furthermore, recent studies have demonstrated that the vulnerability to radiation increases dramatically with decreasing age (Rossi et al, 2016) [17] [19].…”

Section: Radiation-induced Health Riskmentioning

confidence: 98%

Strategies to Improve CT Dose Optimization for Hybrid PET/CT Imaging

Yaseen¹,

Radzi²,

Almohiy³

et al. 2021

OJMI

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Background: To evaluate whether current dose reduction strategies for the CT component of hybrid Positron Emission Tomography-Computed Tomography (PET/CT) systems could reduce patient dose with maintaining adequate image quality for PET/CT studies. Materials and Methods: Literature survey was initially based on the selection of keywords and years of publication to identify potentially relevant articles, then the further search was conducted on the authors and references from these articles. The abstract of each article was first appraised to decide whether the content was relevant to this research question. The articles were classified into five groups: studies on dosimetry, studies on radiation-induced diseases, studies on dose reduction methods for CT-based attenuation correction (CTAC), studies on dose reduction methods for CT localization, and studies on reducing the need for a full-dose diagnostic CT in PET/CT imaging. 58 peer-reviewed articles were selected and appraised and 29 articles were used to compose this literature review. Results: The published nuclear medicine and medical physics literature were reviewed. CT dose contributed 47% -81% of the total effective dose of a standard PET/CT study and was associated with radiation-induced diseases. The dose reduction techniques were extracted and divided into three categories: reducing the CT dose for attenuation correction (AC) and localization, selectively localizing CT use, and reducing the need for a full-dose diagnostic CT. Conclusion: Three strategies have been demonstrated, with high potential for reducing patient dose while maintaining an adequate CT image quality, used for CTCA localization and diagnosis, respectively.

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Section: Radiation-induced Health Riskmentioning

confidence: 98%