821 A Low FODMAP Diet Improves Quality of Life, Reduces Activity Impairment, and Improves Sleep Quality in Patients With Irritable Bowel Syndrome and Diarrhea: Results From a U.S. Randomized, Controlled Trial

Eswaran, Shanti; Chey, William D.; Jackson, Kenya; Pillai, Sivaram; Chey, Samuel W.; Han-Markey, Theresa

doi:10.1016/s0016-5085(16)30665-5

Cited by 4 publications

(3 citation statements)

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“…In addition, significant improvements were seen in stool consistency, stool frequency, and urgency compared to usual dietary recommendations for IBS. Significant improvements in quality of life measures, as well as anxiety were seen in the low FODMAP diet compared to usual dietary recommendations for IBS . The primary endpoints were negative in both trials that utilized an active comparator and dietitian‐directed dietary interventions, highlighting some of the limitations of the low FODMAP diet in the clinical setting (see below).…”

Section: Evidence Of Clinical Benefitmentioning

confidence: 99%

Low FODMAP in 2017: Lessons learned from clinical trials and mechanistic studies

Eswaran

2017

Neurogastroenterology Motil

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Given the prevalence of irritable bowel syndrome (IBS) and the suboptimal response to most therapeutic approaches, there has been increasing interest in and adoption of dietary treatment strategies, such as the low Fermentable Oligo-, Di-, & Mono-Saccharides and Polyols (FODMAP) diet. FODMAPs are a diverse group of carbohydrates that exert effects in the gastrointestinal tract not only via fermentation but likely via alterations in the microbiota, metabolome, permeability, and intestinal immunity as well. Clinical evidence for efficacy of this diet is mounting, but there are significant questions regarding short- and long-term safety and effects on the microbiota and nutrition that remain unanswered. This review article interprets the recent findings reported in this issue of Neurogastroenterology and Motility and summarizes the mechanistic and clinical efficacy data of the low FODMAP diet in IBS patients to date.

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Section: Evidence Of Clinical Benefitmentioning

confidence: 99%

Low FODMAP in 2017: Lessons learned from clinical trials and mechanistic studies

Eswaran

2017

Neurogastroenterology Motil

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“…A pesar de que los resultados de la dieta FODMAPs son inciertos y contradictorios, algunos estudios han demostrado mejoría de los síntomas y la calidad de vida (200)(201)(202), otros que dietas bajas en FODMAPs no tienen ningún impacto en la mejoría de los síntomas o en la calidad de vida de los pacientes (201)(202)(203)(204)(205)(206)(207)(208)(209)(210).…”

Section: Otras Opcionesunclassified

Síndrome de intestino irritable (SII): Nuevos conceptos en 2023.

P.²,

2022

Med.

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El síndrome de intestino irritable, considerado antes como un trastorno funcional, forma actualmente parte del grupo de los trastornos de la interacción del eje intestino-cerebro, una enfermedad orgánica que se identifica clínicamente por la presencia de dolor abdominal recurrente y alteración en la frecuencia o consistencia de las heces. Es una patología multifactorial con impacto negativo en la calidad de vida y hasta el momento, incurable. El objetivo del tratamiento es controlar los síntomas, lo que representa un alto costo para los servicios de salud a nivel mundial. El presente artículo revisa la epidemiología, fisiopatología, el tratamiento y algunos posibles factores relacionados como las alteraciones en la motilidad gastrointestinal, hipersensibilidad visceral, inflamación intestinal, alteración de la microbiota intestinal o disbiosis, sobrecrecimiento bacteriano y la respuesta inmunológica a la dieta.

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“…Indeed, our study provides the first randomised controlled trial evidence to suggest that the efficacy of gut‐directed hypnotherapy for treating symptoms of irritable bowel syndrome (IBS) is comparable to the low FODMAP diet. This finding is substantial given the strong evidence of efficacy for the low FODMAP diet and its superiority to traditional dietary advice …”

mentioning

confidence: 98%

Editorial: gut‐directed hypnotherapy or low FODMAP diet for the treatment of irritable bowel syndrome? Authors' reply

Peters

Yao

Philpott

et al. 2016

Aliment Pharmacol Ther

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821 A Low FODMAP Diet Improves Quality of Life, Reduces Activity Impairment, and Improves Sleep Quality in Patients With Irritable Bowel Syndrome and Diarrhea: Results From a U.S. Randomized, Controlled Trial

Cited by 4 publications

References 0 publications

Low FODMAP in 2017: Lessons learned from clinical trials and mechanistic studies

Low FODMAP in 2017: Lessons learned from clinical trials and mechanistic studies

Síndrome de intestino irritable (SII): Nuevos conceptos en 2023.

Editorial: gut‐directed hypnotherapy or low FODMAP diet for the treatment of irritable bowel syndrome? Authors' reply

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