8 the Use of Annexin v Magnetic-Activated Cell Sorting to Separate Apoptotic Sperm From the Ejaculate of Stallions

With the increasing reproductive issues in all living beings worldwide, numerous problems related to fertility have emerged. Concurrently, the rising global population rates have led to a situation where the available food resources cannot meet the demand. Environmental factors, genetics, age, nutrition, stress, and global changes are some of the reasons that lead to infertility problems. Efforts are still underway to find methods in vivo or in vitro studies to eliminate reproductive problems by preventing structural abnormalities or changes in germ cells. In recent years, some nanoparticles have been utilized to address infertility issues caused by hormonal imbalances, metabolic disorders, or abnormalities in gamete cells, aiming to perform manipulations that could positively impact fertilization. Nanoparticles, used at non-toxic levels, have shown positive responses in fertility. Particularly in spermatological studies, nanoantioxidants have been observed to reduce reactive oxygen species, consequently preventing oxidative stress. Additionally, they are reported to benefit motility and sperm viability, while preserving DNA and gene expression. This section provides important insights into the potential of nanobiotechnology in addressing infertility issues in the years to come.

Section: Figure 1 Schematic Diagram Of Nanopurification Of Semensupporting

confidence: 57%

Nanotechnology in the Treatment of Infertility

Narlıçay,

Kıvrak

2023

Section: Figure 1 Schematic Diagram Of Nanopurification Of Semensupporting

confidence: 57%

“…In this investigation, only 46.3% of the sperm were retrieved using MACS®. More study is needed to determine if MACS® can strengthen sperm quality in infertile stallions and freeze-thawing of sperm (da Silva et al, 2010).…”

Section: Figure 1 Schematic Diagram Of Nanopurification Of Semenmentioning

confidence: 99%

The Positive Effects of In Vivo/In Vitro Suplementation of Nanoparticles on Semen

Koca

2023

Nanoparticles (NPs) are small size molecules. It is divided into organic and inorganic. Organic NPs have many clinical uses, from inoculation to homeostasis, long-term storage and delivery to the system, and absorption of topically used drugs into the skin. Inorganic NPs can be used in intraoperative lymphatic scanning, tumors, and anemia treatments. NPs have a favorable effect on sperm motility, kinematic parameters or membrane integrity rates, they can also be used as antibacterial, antiviral and antifungal in genital organ diseases. There are many studies in which the addition of NPs can be beneficial or harmful to sperm. Researchers have stated that it may be beneficial or cytotoxic depending on in vivo (such as airway, skin or injection) or in vitro use. It has been reported that NPs have positive effects on motility, kinematic parameters, plasma membrane integrity, DNA damage and acrosomal integrity and can be used as an antioxidant. In addition, it has been reported that it can be used in sexsorting, bioimaging and nanopurification, and that more studies on NPs will increase in the coming years.

Section: Figure 1 Schematic Diagram Of Nanopurification Of Semensupporting

confidence: 57%

New Technology in Embryo Manipulations «Nano-Materials»

Turhan,

Turhan

2023

Embryo manipulations have experienced significant increases in recent years. This has led to the development of new methods for the creation of reproductive technologies. When it comes to changing the genetic material of embryonic beings in multiple species– humans especially– there's a particular term involved. It's called nanotechnology and it's quickly becoming an ultra-important area of study. The medical, electricity and energy industries all stand to benefit from its broad range of applications. That's because this revolutionary process involves manipulating materials in a super small size. It involves altering materials at the nanoscale. Nanotechnology offers a range of uses in numerous sectors like medical electronics and energy. In medicine, nanotechnology has led to significant advances in the delivery of drug imaging and diagnosis. Besides, it has facilitated the manipulation of embryos in a new manner. The utilization of nanomaterials in embryo manipulations has the benefit of increasing embryo implantation rates through assisted reproductive technology (ART) and the implantation rates of in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI). Another advantage of using nanomaterials in embryo modification is that genetic abnormalities are reduced. Other than that the relevance of nanoparticles has led to new potential in the field of artificial insemination. This book explains the most recent breakthroughs in the modification of human and animal embryos as well as the numerous types of nanoparticles and the benefits of their use in the process. Additionally, the book discusses the applications of nanoparticles in IVF and gene editing. This book also discusses ethical concerns issues and limitations of the new technology it also highlights the potential impact on the field of reproductive medicine.