794c Pancreatic Serous Cystadenoma Related Mortality Is Nil. Results of a Multinational Study Under the Auspices of the International Association of Pancreatology and the European Pancreatic Club

Jaïs, Bénédicte; Rebours, Vinciane; Kim, Myung–Hwan; Ha, Yeonjung; Kimura, Wataru; Hirai, Ichiro; Marchegiani, Giovanni; Castillo, Carlos Fernández‐del; Gomatos, Ilias P.; Neoptolemos, John P.; Sperti, Cosimo; Milanetto, Anna Caterina; Wang, Huaizhi; Ricci, Claudio; Casadei, Riccardo; Pererva, L.; Kopchak, Kostiantyn; Matsumoto, Ippei; Shinzeki, Makoto; Chiaro, Marco Del; Segersvärd, Ralf; acuna, Isis K. Araujo; Vaquero, Eva C.; Angiolini, Maria Rachele; Zerbi, Alessandro; Hilal, Mohammad Abu; Burkert, Julia; Lee, Chang Geun; Ouaïssi, Mehdi; Sastre, B.; Petrone, Maria Chiara; Arcidiacono, Paolo Giorgio; Lévy, Philippe

doi:10.1016/s0016-5085(14)60485-6

Cited by 8 publications

(6 citation statements)

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“…Despite the improvement of imaging examinations and intracystic fluid analysis, the diagnosis of SCA often remains uncertain, and lesions larger than 2 cm are frequently surgically resected in asymptomatic patients [3]. In a large retrospective multinational study on 2622 patients with SCA, 36 % of them underwent surgery for an uncertain diagnosis [11]. This approach remains inappropriate given the fact that surgery is associated with substantial morbidity and mortality [12] and that simple surveillance could be sufficient [13].…”

Section: Discussionmentioning

confidence: 99%

A novel approach to the diagnosis of pancreatic serous cystadenoma: needle-based confocal laser endomicroscopy

et al. 2014

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Section: Discussionmentioning

confidence: 99%

A novel approach to the diagnosis of pancreatic serous cystadenoma: needle-based confocal laser endomicroscopy

et al. 2014

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“…Jaundice, due to bile duct compression, is infrequent [18]. A recently published multinational, retrospective study including 598 patients with a diagnosis of SCA showed that nonspecific abdominal pain was reported in 29% of cases, diabetes mellitus in 7% of patients and, finally, bilio-pancreatic symptoms, including typical pancreatic pain, acute pancreatitis, jaundice and steatorrhoea in 7% of cases [19]. Tumor rupture, hemoperitoneum and acute surgical abdomen have also been described [20,21].…”

Section: Clinical Presentationmentioning

confidence: 99%

“…Indeed, SCA-related mortality is nil, whereas operative mortality is not. A multinational, retrospective study involving 58 centers in 18 countries showed that the post-operative mortality reported in patients that underwent pancreatic surgery for SCA was 0.8%, while the SCA related mortality was 0% in patients with a median follow-up period of 3.1 years [19]. Therefore, this latter strategy is highly recommended, and surgery should only be considered in a subset of patients with clear indications.…”

Section: Prognosis Treatment and Follow-up Strategiesmentioning

confidence: 99%

Management of serous cystic neoplasms of the pancreas

Antonini

Fuccio

Fabbri

et al. 2014

Expert Review of Gastroenterology & Hepatology

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Pancreatic serous cystadenomas are uncommon benign tumours that are often found incidentally on routine imaging examinations. Radiological imaging techniques alone have proven to be suboptimal to fully characterize cystic pancreatic lesions. Endoscopic ultrasound, with the addition of fine-needle aspiration in difficult cases, has showed greater diagnostic accuracy than conventional imaging techniques. The best management strategy of these neoplasms is still debated. Surgery should be limited only to symptomatic and highly selected cases and most of the patients should only be strictly monitored. In the current paper, we provide an updated overview on pancreatic serous cystadenomas, focusing our attention on epidemiology, clinical characteristics and diagnostic evaluation; finally, we also discuss different management strategies and areas for future research.

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“…4 Those with no, or very low malignant potential, such as pseudocysts and SCAs, require minimal or no follow up in the absence of symptoms related to the cyst. 5 Solid-pseudopapillary neoplasms (SPN) are low-grade malignant neoplasms, and surgically resection is recommended. 6 Invasive adenocarcinoma occurs in between 4% to 16% of surgically resected MCNs in modern studies.…”

Section: Introductionmentioning

confidence: 99%

Analysis of Pancreatic Cyst Fluid

Ngamruengphong

Lennon

2016

Surgical Pathology Clinics

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Synopsis Pancreatic cysts are extremely common, and are identified in between 2% to 13% on abdominal imaging studies. The majority of pancreatic cysts are pseudocysts, serous cystic neoplasms (SCNs), mucinous cystic neoplasms (MCNs) or intraductal papillary mucinous neoplasm (IPMNs). The management of pancreatic cysts depends on whether a cyst is benign, has malignant potential, or harbors high-grade dysplasia or invasive carcinoma. The diagnosis of pancreatic cysts, and assessment of risk of malignant transformation, incorporates a number of factors including clinical history, computed tomography (CT), magnetic resonance imaging (MRI), endoscopic ultrasound and fine needle aspiration of cyst fluid (EUS-FNA). This paper reviews the cyst fluid markers which are currently used, as well as promising markers under development.

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794c Pancreatic Serous Cystadenoma Related Mortality Is Nil. Results of a Multinational Study Under the Auspices of the International Association of Pancreatology and the European Pancreatic Club

Cited by 8 publications

References 0 publications

A novel approach to the diagnosis of pancreatic serous cystadenoma: needle-based confocal laser endomicroscopy

A novel approach to the diagnosis of pancreatic serous cystadenoma: needle-based confocal laser endomicroscopy

Management of serous cystic neoplasms of the pancreas

Analysis of Pancreatic Cyst Fluid

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