64-detector row CT cystography with virtual cystoscopy in the detection of bladder carcinoma: preliminary experience in selected patients

Panebianco, Valeria; Osimani, Marcello; Lisi, Danilo; Santucci, E.; Ciccariello, Mauro; Iori, S; Catalano, Carlo; Passariello, Roberto

doi:10.1007/s11547-008-0350-x

Cited by 16 publications

(7 citation statements)

References 26 publications

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“…This consideration is, however, based on data published by Sadow et al [20], which appear more encouraging than those observed in our series. Recently, the use of CT cystography with virtual cystography has been proposed [21]. In selected patients, this examination showed a high level of diagnostic accuracy, higher than that of conventional CT urography, especially in lesions <5 mm.…”

Section: Discussionmentioning

confidence: 99%

“…ematuria microscopica ma a basso rischio per neoplasia vescicale, sebbene questa considerazione si basi sui dati pubblicati da Sadow et al [20], che risultano più rassicuranti di quelli della nostra casistica. Recentemente è stato proposto anche l'uso di un esame di cistografia TC con cistografia virtuale [21]. Tale esame ha dimostrato un'elevata accuratezza diagnostica in pazienti selezionati, maggiore rispetto all'esame uro-TC convenzionale, particolarmente nelle lesioni sotto i 5 mm, va peraltro rilevato come tale esame sia piuttosto indaginoso e soprattutto come non risponda completamente al quesito clinico di ricerca della causa di ematuria, limitandosi allo studio vescicale, agevolmente, seppur invasivamente effettuato dagli urologi, mentre le alte vie escretrici rimangono escluse dalla valutazione.…”

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64-Slice CT urography: 30 months of clinical experience

et al. 2010

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Section: Discussionmentioning

confidence: 99%

Section: Discussionunclassified

64-Slice CT urography: 30 months of clinical experience

et al. 2010

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“…The accuracy of detecting bladder lesions (<1 cm) by computed tomography virtual cystoscopy (CTVC) has been variously reported ranging within 60–100% [ 7 , 10 – 12 ]. Even bladder lesions <5 mm have also been reportedly detected by some authors utilizing CTVC [ 13 – 15 ], while others have found the visualization of such lesions to be difficult [ 10 ]. This technology is considered safe for bladder cancer follow-up with detection rates comparable to conventional cystoscopy.…”

Section: Introductionmentioning

confidence: 99%

Can CT Virtual Cystoscopy Replace Conventional Cystoscopy in Early Detection of Bladder Cancer?

Abrol

Jairath

Ganpule

et al. 2015

Advances in Urology

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Aim. To correlate findings of conventional cystoscopy with CT virtual cystoscopy (CTVC) in detecting bladder tumors and to evaluate accuracy of virtual cystoscopy in early detection of bladder cancer. Material and Method. From June 2013 to June 2014, 50 patients (46 males, four females) with history and investigations suggestive of urothelial cancer, with mean age 62.76 ± 10.45 years, underwent CTVC by a radiologist as per protocol and subsequently underwent conventional cystoscopy (CPE) the same day or the next day. One urologist and one radiologist, blinded to the findings of conventional cystoscopy, independently interpreted the images, and any discrepant readings were resolved with consensus. Result. CTVC detected 23 out of 25 patients with bladder tumor(s) correctly. Two patients were falsely detected as negative while two were falsely labeled as positive in CTVC. Virtual and conventional cystoscopy were comparable in detection of tumor growth in urinary bladder. The sensitivity, specificity, positive predictive value, and negative predictive value of virtual cystoscopy were 92% each. Conclusion. CTVC correlates closely with the findings of conventional cystoscopy. Bladder should be adequately distended and devoid of urine at the time of procedure. However, more studies are required to define the role of virtual cystoscopy in routine clinical practice.

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“…However, disadvantages such as patient discomfort, risk of urinary sepsis, and possible injury of the urethra with subsequent urethral stenosis render this procedure invasive not to mention expensive considering the long follow-up of bladder cancer patients [1, 3–5]. …”

Section: Introductionmentioning

confidence: 99%

The Role of Virtual Cystoscopy, after Multidetector Computed Tomography Imaging Reconstruction without the Use of Contrast Medium, in the Diagnosis and Evaluations of Bladder Tumors: Preliminary Study

Kalokairinou

Ploumidis

Kalogeropoulos

et al. 2014

Advances in Urology

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Introduction. Although conventional cystoscopy is considered to be the gold standard for diagnosis and follow-up of bladder tumors, it remains an invasive and costly procedure. With the advent of the multidetector CT (MDCT) scanners supported by specialized software virtual cystoscopy (VC) is possible. We assess the role of VC in diagnosing and evaluating bladder lesions. Materials and Methods. Between September 2010 and October 2011, 25 consecutive patients with cystoscopically confirmed bladder tumor underwent VC. The radiologists involved in this prospective study were blinded to the exact findings. After draining any residual urine with a catheter, the bladder was retrogradely insufflated with 200–600 cc of air. No intravenous or intravesical contrast was used. MDCT scan was performed in supine and prone positions and three-dimensional reconstruction of the urinary bladder was performed. Results. The examination was well tolerated by all patients with no complications. In total, 43 lesions were detected both with conventional cystoscopy and VC. Tumor size measured by CT ranged from 3 to 80 mm in diameter. The pathological report revealed noninvasive transitional cell carcinomas in all cases. Conclusion. VC has promising results in detecting exophytic bladder lesions. In the future it could be part of the diagnostic algorithm for bladder tumors.

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64-detector row CT cystography with virtual cystoscopy in the detection of bladder carcinoma: preliminary experience in selected patients

Abstract: VC and CTC with 64-slice CT are promising diagnostic techniques for bladder cancers measuring 1-5 mm. Further studies on larger patient populations are required to validate our results.

Cited by 16 publications

References 26 publications

64-Slice CT urography: 30 months of clinical experience

64-Slice CT urography: 30 months of clinical experience

Can CT Virtual Cystoscopy Replace Conventional Cystoscopy in Early Detection of Bladder Cancer?

The Role of Virtual Cystoscopy, after Multidetector Computed Tomography Imaging Reconstruction without the Use of Contrast Medium, in the Diagnosis and Evaluations of Bladder Tumors: Preliminary Study

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