Can CT Virtual Cystoscopy Replace Conventional Cystoscopy in Early Detection of Bladder Cancer?

Abstract

Aim. To correlate findings of conventional cystoscopy with CT virtual cystoscopy (CTVC) in detecting bladder tumors and to evaluate accuracy of virtual cystoscopy in early detection of bladder cancer. Material and Method. From June 2013 to June 2014, 50 patients (46 males, four females) with history and investigations suggestive of urothelial cancer, with mean age 62.76 ± 10.45 years, underwent CTVC by a radiologist as per protocol and subsequently underwent conventional cystoscopy (CPE) the same day or the next day. One urologist and one radiologist, blinded to the findings of conventional cystoscopy, independently interpreted the images, and any discrepant readings were resolved with consensus. Result. CTVC detected 23 out of 25 patients with bladder tumor(s) correctly. Two patients were falsely detected as negative while two were falsely labeled as positive in CTVC. Virtual and conventional cystoscopy were comparable in detection of tumor growth in urinary bladder. The sensitivity, specificity, positive predictive value, and negative predictive value of virtual cystoscopy were 92% each. Conclusion. CTVC correlates closely with the findings of conventional cystoscopy. Bladder should be adequately distended and devoid of urine at the time of procedure. However, more studies are required to define the role of virtual cystoscopy in routine clinical practice.

Recent advances in three-dimensional ultrasound virtual cystoscopy in modeling and local staging for urothelial carcinoma with histopathological correlation: a cohort prospective study

“…Formerly, Abrol et al . 17 found that combining evaluated virtual rendered images with multiplanar images could provide valuable information for the mural and extraluminal mass extensions, such as mural and extravesical invasion, distal ureteral obstruction, and pressure of the neighbouring organs.…”

Role of multidetector CT virtual cystoscopy compared to conventional cystoscopy in the diagnosis of urinary bladder neoplasms

“…Painless hematuria is one of the typical signs of bladder cancer, and one of the most important problems with urinary bladder tumors is disease recurrence. Therefore, close monitoring of the patient is required [6]. CT is the usually recommended radiologic approach to assess hematuria, and for CT to depict even small bladder lesions, optimal imaging conditions including adequate bladder distention and thin-slice scanning must be fulfilled [7].…”

Nuevas herramientas para el diagnóstico del cáncer de vejiga

“…Vining en la que se propone una reconstrucción por tomografía de la vejiga, (27) esta técnica ha sido adaptada para lograr una visualización anatómica vesical semejante a la lograda bajo visón directa. (28) La toma de esta imagen tiene un protocolo particular que puede variar de acuerdo con el del centro donde se tome la imagen. Inicialmente el paciente debe evacuar completamente la vejiga.…”

“…Radiología. 2017.Se ha reportado una sensibilidad del 89-100% y especificidad del 80-87%,(28)(29)(30) para el diagnóstico de CV con cistoscopia virtual, en comparación con 87-100% y 75-95% de la cistoscopia óptica, respectivamente (12). La sensibilidad disminuye en lesiones menores de 3 cm al igual que en la sospecha de tumor in situ, en estos casos es más fiable la visualización directa de las lesiones (29).…”