52 Defining host T-cell responses in oral candidiasis

Rethinking T cell immunity in oropharyngeal candidiasis

“…Patients with impaired cell-mediated immunity, including those with advanced HIV infection, are highly susceptible to OPC. On page 299 of this issue, Conti et al show that defense against OPC is more dependent on Th17-than Th-1-type immunity ( 6 ). In this Commentary, we discuss this fi nding in light of unanswered questions about the pathogenesis of HIVassociated OPC.…”