51 Differences in sodium intake determine the blood pressure phenotype in pregnant rats

Mistry, Hiten D.; Eisele, Nicole; Escher, Geneviève; Rudloff, Stefan; Gennari-Moser, Carine; Mohaupt, Markus

doi:10.1016/j.preghy.2016.08.133

Cited by 1 publication

(2 citation statements)

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“…HA acts as a ligand for three main cell surface receptors: CD44 receptor, hyaluronate‐mediated motility receptor (RHAMM) and Intercellular adhesion molecule 1 (ICAM‐1), which perform various functions. [ 71 ] Among these, CD44, a transmembrane glycoprotein (molecular weight of 85–200 kDa), is the most largely distributed cell surface recognized receptor for HA binding. [ 72,73 ] CD44 isoforms take part in various signaling pathways including morphogenesis, proliferation, and wound repair, and growing evidence suggests that CD44 receptors overexpression are involved in tumor progression and subsequently in the metastasis starting process.…”

Section: Surface Functionalization With Hamentioning

confidence: 99%

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Advances in Hyaluronic‐Acid‐Based (Nano)Devices for Cancer Therapy

Sala

Fabozzi

Gennaro

et al. 2021

Macromolecular Bioscience

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Cancer is the main cause of fatality all over the world with a considerable growth rate. Many biologically active nanoplatforms are exploited for tumor treatment. Of nanodevices, hyaluronic acid (HA)‐based systems have shown to be promising candidates for cancer therapy due to their high biocompatibility and cell internalization. Herein, surface functionalization of different nanoparticles (NPs), e.g., organic‐ and inorganic‐based NPs, is highlighted. Subsequently, HA‐based nanostructures and their applications in cancer therapy are presented.

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Section: Surface Functionalization With Hamentioning

confidence: 99%

“…For instance, lower pH and overexpression of some biologically active molecules differentiate tumor cells from normal cells. [ 71 ] Insight of this, different kinds of nanosized structures containing a wide set of cargo have been modified with biologically active molecules, e.g. HA, to improve the targeted delivery.…”

Section: Surface Functionalization With Hamentioning

confidence: 99%