5-phenyl-2H-tetrazol-2-ylmethyl ketones in the synthesis of tetrazolylalkanols and tetrazolyl(hydroxy)alkylphosphonates

The electrochemically enabled α-C(sp3)–H azolation of ketones

“…2 In this case, the reaction of tetrazoles with α-haloaryl ketones provides a classical method for installing a tetrazole group into the C(sp 3 ) position of the ketones. However, these transformations are generally limited to pre-equipped haloaryl ketone substrates, such as chlorine 3 and bromine. 4 Additionally, an excess of alkali is added to neutralize the hydrogen halide produced in the reaction.…”