5-Methylcoumarin derivatives from Aphyllocladus denticulatus

Zdero, Christa; Bohlmann, Ferdinand; Niemeyer, Hermann M.

doi:10.1016/0031-9422(88)80452-7

Search citation statements

Order By: Relevance

Paper Sections

Select...

Introduction1

Citation Types

Supporting

Mentioning

Contrasting

Year Published

1989

2017

Publication Types

Select...

Article3

Book3

Relationship

Self Cite0

Independent6

Authors

Journals

Cited by 13 publications

(2 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…260 However, isofraxoside which melts more than 50 "C higher has already been deduced to have this structure. ( -)-8-Methoxyobliquin (374)…”

mentioning

confidence: 99%

Coumarins

Murray¹

1989

Nat. Prod. Rep.

122

View full text Add to dashboard Cite

“…260 However, isofraxoside which melts more than 50 "C higher has already been deduced to have this structure. ( -)-8-Methoxyobliquin (374)…”

mentioning

confidence: 99%

Coumarins

Murray¹

1989

Nat. Prod. Rep.

122

View full text Add to dashboard Cite

“…Previous investigations on the chemical composition of Aphyllocladus revealed the presence of 5‐methylcoumarin derivatives in A . denticulatus . In another study with A .…”

Section: Introductionmentioning

confidence: 86%

Chemical Composition and Biological Prospects of Essential Oils and Extracts of Aphyllocladus spartioides Growing in Northwest Argentina

Celaya

Viturro

Silva

2017

Chemistry & Biodiversity

View full text Add to dashboard Cite

Aphyllocladus spartioides Wedd. is a native and aromatic herb used in traditional medicine, however it is still poorly investigated. In this work, the volatile profile of A. spartioides growing in Hornillos-Northwest Argentina was determined by GC/MS/FID and the phenolic compounds of hydroethanolic and decoction extracts were analyzed by HPLC-DAD. The antibacterial potential, antioxidant activity and α-glucosidase inhibition activity were checked by in vitro assays. The volatile profile allowed the identification of 68 compounds, being α-pinene and cadinene the main ones. Eighteen phenolics were identified, isorhamnetin derivatives and different phenolic acid derivatives were found in higher amounts, mainly in the hydroethanolic extract. A concentration-dependent activity was noticed against DPPH , O2·-, ·NO and α-glucosidase, these activities being reported for the first time. Hydroethanolic extract was most active against DPPH , NO and α-glucosidase (IC = 79, 206 and 181 μg/ml). Decoction extract proved to be better against O2·- (IC = 20 μg/ml). Regarding the antibacterial activity, hydroethanolic extract was more active compared with decoction and essential oil. MICs of 0.3 - 0.6 mg/ml were obtained against Staphylococcus aureus, Bacillus cereus, and Micrococcus luteus. Results suggest that the extracts of A. spartioides from Northwest Argentina may be interesting to use as a source of natural antioxidants/antimicrobials for pharmaceutical incorporations or food supplementation.

show abstract

Miscellaneous Sesquiterpenes

Atta-ur-Rahman

Ahmad

1992

13c-NMR of Natural Products

View full text Add to dashboard Cite

5-Methylcoumarin derivatives from Aphyllocladus denticulatus

Cited by 13 publications

References 3 publications

Coumarins

Coumarins

Chemical Composition and Biological Prospects of Essential Oils and Extracts of Aphyllocladus spartioides Growing in Northwest Argentina

Miscellaneous Sesquiterpenes

Contact Info

Product

Resources

About