“…We next tested the biofilm-inhibition and -dispersion activities of select compounds, looking to evaluate how these analogues compared with the already potent dichlorinated oxazolidinone derivatives prepared previously. [34] Most of the alkyl derivatives tested (5,7,9,10,12,14,18,22, and 23) possessed low levels of inhibition and dispersion, with none of these new analogues reaching 50 % activity at 40 mm (Figure 2 C). Importantly, 15 and 24, the two most active compounds in our MIC assays, were able to inhibit and disperse biofilms in a dose-dependent manner.…”