5,9,11-Trihydroxy-2,2-dimethyl-3-(2-methylbut-3-en-2-yl)pyrano[2,3-a]xanthen-12(2H)-one from the Stem Bark of Calophyllum tetrapterum Miq.

Tjahjandarie, Tjitjik Srie; Saputri, Ratih Dewi; Tanjung, Mulyadi

doi:10.3390/m936

Cited by 3 publications

(3 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…5,9,11-Trihydroxy-10-(2 -hydroxy-3 -methylbut-3 -en-1-yl)-2,2-dimethyl-3-(2 -methylbut-3 -en-2 -yl)-2H,12H-pyrano[2,3-a]xanthen-12-onewas isolated as a yellow solid, and its UV absorption maxima at λ max 245, 268, and 320 nm which is characteristic of xanthone chromophore [2]. Based on HRESIMS (see data supplementary Figure S1), compound 1 showed deprotonated molecule ion [M − H] − at m/z 477.1917corresponding to the molecular formula C 28 H 30 O 7 .…”

Section: Resultsmentioning

confidence: 99%

“…This plant isendemic to Kalimantan Island, Indonesia. This genus has been shown to possess a number of secondary metabolites such as xanthones [1][2][3], coumarins [4,5], and chromanone acids [6,7]. Many of these compounds have shown a wide range of biological and pharmacological properties such as anti-HIV [8,9], anticancer [10,11], and antimalarial properties [12].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

5,9,11-Trihydroxy-10-(2″-hydroxy-3″-methylbut-3″-en-1-yl)-2,2-dimethyl-3-(2′-methylbut-3′-en-2′-yl)-2H,12H-pyrano[2,3-a]xanthen-12-one from Calophyllum pseudomole

Tanjung¹,

Saputri²,

Tjahjandarie³

2017

Molbank

Self Cite

View full text Add to dashboard Cite

Abstract:A new pyranocoumarin, namely 5,9,11-trihydroxy-10-(2 -hydroxy-3 -methylbut-3 en-1-yl)-2,2-dimethyl-3-(2 -methylbut-3 -en-2 -yl)-2H,12H-pyrano[2,3-a]xanthen-12-one 1, was isolated from the stem barkof Calophyllum pesudomole. The structure of compound 1 was elucidated based on its ultaraviolet (UV); infrared (IR); high resolution electro spray ionization mass spectrometry (HRESIMS); 1D and 2D nuclear magnetic resonance (NMR) spectral data.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

5,9,11-Trihydroxy-10-(2″-hydroxy-3″-methylbut-3″-en-1-yl)-2,2-dimethyl-3-(2′-methylbut-3′-en-2′-yl)-2H,12H-pyrano[2,3-a]xanthen-12-one from Calophyllum pseudomole

Tanjung¹,

Saputri²,

Tjahjandarie³

2017

Molbank

Self Cite

View full text Add to dashboard Cite

show abstract

“…Penentuan uji aktivitas antikanker senyawa 1-2 terhadap sel kanker murin leukemia P-388 menggunakan metode MTT assay (Tanjung, 2013;Tjahjandarie, 2017). Jumlah sel yang terinhibisi oleh masing-masing senyawa 1 dan 2 diukur serapannya dengan menggunakan microplate reader pada λ 540 nm setelah diinkubasi selama 24 jam dalam incubator CO2 pada suhu 37º C. Senyawa hasil isolasi dengan variasi konsentrasi 1000; 100; 30; 10; 3; 1; 0,3 dan 0,1 µg/ml dengan perlakuan triplo diuji pada kultur sel murin leukemia P-388.…”

Section: Uji Aktivitas Antikanker Terhadap Sel Murin Leukemia P-388unclassified

Alkaloid Kuinolin dari Melicope denhamii dan Uji Aktivitas Antikankernya

Saputri¹,

Tjahjandarie

Tanjung

2018

J. Sains Kes.

View full text Add to dashboard Cite

show abstract

Xanthones: Biosynthesis and Trafficking in Plants, Fungi and Lichens

Badiali

Petruccelli

Brasili

et al. 2023

Plants

View full text Add to dashboard Cite

Xanthones are a class of secondary metabolites produced by plant organisms. They are characterized by a wide structural variety and numerous biological activities that make them valuable metabolites for use in the pharmaceutical field. This review shows the current knowledge of the xanthone biosynthetic pathway with a focus on the precursors and the enzymes involved, as well as on the cellular and organ localization of xanthones in plants. Xanthone biosynthesis in plants involves the shikimate and the acetate pathways which originate in plastids and endoplasmic reticulum, respectively. The pathway continues following three alternative routes, two phenylalanine-dependent and one phenylalanine-independent. All three routes lead to the biosynthesis of 2,3′,4,6-tetrahydroxybenzophenone, which is the central intermediate. Unlike plants, the xanthone core in fungi and lichens is wholly derived from polyketide. Although organs and tissues synthesizing and accumulating xanthones are known in plants, no information is yet available on their subcellular and cellular localization in fungi and lichens. This review highlights the studies published to date on xanthone biosynthesis and trafficking in plant organisms, from which it emerges that the mechanisms underlying their synthesis need to be further investigated in order to exploit them for application purposes.

show abstract

5,9,11-Trihydroxy-2,2-dimethyl-3-(2-methylbut-3-en-2-yl)pyrano[2,3-a]xanthen-12(2H)-one from the Stem Bark of Calophyllum tetrapterum Miq.

Cited by 3 publications

References 14 publications

5,9,11-Trihydroxy-10-(2″-hydroxy-3″-methylbut-3″-en-1-yl)-2,2-dimethyl-3-(2′-methylbut-3′-en-2′-yl)-2H,12H-pyrano[2,3-a]xanthen-12-one from Calophyllum pseudomole

5,9,11-Trihydroxy-10-(2″-hydroxy-3″-methylbut-3″-en-1-yl)-2,2-dimethyl-3-(2′-methylbut-3′-en-2′-yl)-2H,12H-pyrano[2,3-a]xanthen-12-one from Calophyllum pseudomole

Alkaloid Kuinolin dari Melicope denhamii dan Uji Aktivitas Antikankernya

Xanthones: Biosynthesis and Trafficking in Plants, Fungi and Lichens

Contact Info

Product

Resources

About