4D-CT angiography versus 3D-rotational angiography as the imaging modality for computational fluid dynamics of cerebral aneurysms

Cancelliere, N; Najafi, Mehdi; Brina, Olivier; Bouillot, Pierre; Vargas, María Isabel; Lövblad, Karl-Olof; Krings, Timo; Pereira, Vítor Mendes; Steinman, David A.

doi:10.1136/neurintsurg-2019-015389

Cited by 22 publications

(8 citation statements)

References 29 publications

(43 reference statements)

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“…Four-dimensional CT (4D-CT) adds a time axis to three-dimensional data and allows continuous CT imaging on a timeseries basis. This method has widespread clinical application for assessments such as evaluation of blood ow dynamics [16][17][18][19]. In the eld of orthopedic surgery, this method is expected to improve evaluations of joint dynamics and functions [20].…”

Section: Introductionmentioning

confidence: 99%

Accuracy Verification of 4D-CT Analysis of Knee Joint Movements: A Pilot Study Using a Knee Joint Model and Motion-capture System

Adachi

Kato

Kiyotomo³

et al. 2021

Preprint

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BackgroundFour-dimensional CT(4D-CT) is an advanced imaging method with the ability to acquire kinematic and three-dimensional morphological information. Although its use for analysis of the six degrees of freedom in the knee is expected, its accuracy has not been reported. This study aimed to use the optical motion-capture method to verify the accuracy of 4D-CT analysis of knee joint movement.MethodsOne static CT and three 4D-CT examinations of the knee joint model were obtained. The knee joint model was passively moved in the CT gantry during 4D-CT acquisitions. 4D-CT and static CT examinations were matched to perform 3D-3D registration. An optical motion-capture system recorded the position-posture of the knee joint model simultaneously with the 4D-CT acquisitions. These results were used as the correct answer value, the position-posture measurements using 4D-CT were compared to these values, and the accuracy of the 4D-CT analysis of knee joint movements was quantitatively assessed. ResultsThe position-posture measurements obtained from 4D-CT showed similar tendency to those obtained from the motion-capture system. In the femorotibial joint, the difference in the spatial orientation between the two measurements was 0.7 mm in the X direction, 0.9 mm in the Y direction, and 2.8 mm in the Z direction. The difference in angle was 1.9° in the varus/valgus direction, 1.1° in the internal/external rotation, and 1.8° in extension/flexion. In the patellofemoral joint, the difference between the two measurements was 0.9 mm in the X direction, 1.3 mm in the Y direction, and 1.2 mm in the Z direction. The difference in angle was 0.9° for varus/valgus, 1.1° for internal/external rotation, and 1.3° for extension / flexion. Conclusions4D-CT with 3D-3D registration could record the position-posture of knee joint movements with an error of less than 3 mm and less than 2° when compared with the highly accurate motion-capture system. Knee joint movement analysis using 4D-CT with 3D-3D registration showed excellent accuracy for in vivo applications.

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Section: Introductionmentioning

confidence: 99%

Accuracy Verification of 4D-CT Analysis of Knee Joint Movements: A Pilot Study Using a Knee Joint Model and Motion-capture System

Adachi

Kato

Kiyotomo³

et al. 2021

Preprint

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“…Due to the differences in imaging principle and scanning conditions, different imaging modalities with unique features will show different depictions of aneurysmal structures 5 17–20. In this study, the morphological comparison showed geometric consistency between both imaging techniques for aneurysm complexes.…”

Section: Discussionmentioning

confidence: 60%

“…A possible explanation is due to the non-ICA subgroup with greater differences in TAWSS and smaller differences in PAWSS, but the differences were not statistically significant for TAWSS and PAWSS. Cancelliere et al 20 postulated that hemodynamic results may be affected by flow rates estimated according to the inlet diameter of parent arteries, which varies among different image techniques. Despite showing no statistical difference between 3DRA and silent MRA in average parent vessel diameter (p=0.7615), model comparisons revealed differences in parent vessel models, especially for the distal aneurysms.…”

Section: Discussionmentioning

confidence: 99%

Non-contrast enhanced silent MR angiography to evaluate hemodynamics and morphology of unruptured intracranial aneurysms: a comparative computational fluid dynamics study

Leng²,

Zou³

et al. 2022

J NeuroIntervent Surg

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BackgroundSilent MR angiography (silent MRA) is a new generation of non-contrast enhanced angiography with outstanding advantages in visualizing cerebrovascular lesions and the follow-up after endovascular treatment for intracranial aneurysms (IAs). This study aims to investigate the reliability of silent MRA-based three-dimensional (3D) geometric description and hemodynamic calculation of IAs.Methods19 patients with 23 unruptured IAs, who underwent both silent MRA and 3D rotational angiography (3DRA), were included in this study. Computational fluid dynamics simulations were performed on all patient-specific 3D reconstruction images to compare the morphology and hemodynamics of the two different imaging models for IAs.ResultsSilent MRA models had smaller maximum and perpendicular height (mm), aneurysmal surface area (mm2), and aneurysmal volume (mm3) than 3DRA (p<0.05); the differences of the above parameters between the two models were 9.0±6.2%, 7.7±7.4%, 15.9±13.0%, and 21.4±17.5%, respectively. However, correlation analysis of morphological parameters in various dimensions and model comparison showed good overall consistency in geometrical characteristics between the two models. Moderate coherence was observed between models in time-averaged wall shear stress of aneurysm and parent vessel (TAWSS, PAWSS), aneurysm velocity (AV), parent vessel velocity, and oscillatory shear index (OSI). However, strong correlations were observed among normalized aneurysm wall shear stress (NWSS), low shear area (LSA), inflow concentration index (ICI), and normalized aneurysm velocity (NAV).ConclusionBoth morphological and hemodynamic assessments of IAs for silent MRA are comparable to 3DRA. Additionally, normalized indicators such as NWSS, LSA, ICI, and NAV were better than TAWSS, AV, and OSI in silent MRA-related hemodynamic evaluation.

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“…Compared to classical CTA, with a longer acquisition time or several acquisitions over a given period, 4D-CTA records the influx and efflux of the contrast product and morphological changes of IA within a cardiac cycle when the acquisition is ECG-gated ( 64 ). 4D-CTA is mostly used in the evaluation of hemorrhagic/ischemic stroke and vascular malformations and has been proposed to replace the gold standard 3D-DSA for follow-up imaging since it produces accurate IA geometrics and reliable CFD results when compared to 3DRA ( 65 ).…”

Section: Hemodynamic Imagingmentioning

confidence: 99%

Imaging Modalities for Intracranial Aneurysm: More Than Meets the Eye

Maupu

Lebas

Boulaftali

2022

Front. Cardiovasc. Med.

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Intracranial aneurysms (IA) are often asymptomatic and have a prevalence of 3 to 5% in the adult population. The risk of IA rupture is low, however when it occurs half of the patients dies from subarachnoid hemorrhage (SAH). To avoid this fatal evolution, the main treatment is an invasive surgical procedure, which is considered to be at high risk of rupture. This risk score of IA rupture is evaluated mainly according to its size and location. Therefore, angiography and anatomic imaging of the intracranial aneurysm are crucial for its diagnosis. Moreover, it has become obvious in recent years that several other factors are implied in this complication, such as the blood flow complexity or inflammation. These recent findings lead to the development of new IA imaging tools such as vessel wall imaging, 4D-MRI, or molecular MRI to visualize inflammation at the site of IA in human and animal models. In this review, we will summarize IA imaging techniques used for the patients and those currently in development.

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4D-CT angiography versus 3D-rotational angiography as the imaging modality for computational fluid dynamics of cerebral aneurysms

Cited by 22 publications

References 29 publications

Accuracy Verification of 4D-CT Analysis of Knee Joint Movements: A Pilot Study Using a Knee Joint Model and Motion-capture System

Accuracy Verification of 4D-CT Analysis of Knee Joint Movements: A Pilot Study Using a Knee Joint Model and Motion-capture System

Non-contrast enhanced silent MR angiography to evaluate hemodynamics and morphology of unruptured intracranial aneurysms: a comparative computational fluid dynamics study

Imaging Modalities for Intracranial Aneurysm: More Than Meets the Eye

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