45-year-old man with hypertrophic cardiomyopathy after alcohol ablation, progression to dilated cardiomyopathy (RCD code: III‑1B.8a)

Abstract

Hypertrophic cardiomyopathy (HCM) is the most common inheritable cardiac disorder with an estimated prevalence of 1:500 in the general population. In minority of patients, with the prevalence approximately of 3-5%, HCM progresses into dilated, end-stage or burn-out phase, characterized by LV wall thinning, systolic dysfunction and LV cavity dilatation. We present a case of a 45 year-old man with endstage HCM with postcapillary pulmonary hypertension, who was experimentally treated with sildenafil. It resulted in noticeable clinical and haemodynamical improvement. JRCD 2014; 2 (1): 23-26

Apical hypertrophic cardiomyopathy in an adult (RCD code: III-2A)

“…arterial hypertension, aortic stenosis) [1]. HCM is one of the most common inherited heart disease observed in 1 in 500 of the general adult population and mostly it is caused by mutations in genes encoding the different components of the sarcomere apparatus [2,3]. The phenotypic expression is variable and one of the variant may present as the AHC.…”