441. The Sommelet reaction. Part III. The choice of solvent and the effect of substituents

Angyal, S. J.; Morris, Peter; Tetaz, J. R.; Wilson, J. G.

doi:10.1039/jr9500002141

Cited by 63 publications

(29 citation statements)

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“…The 5-(triethylammoniummethyl) salicylaldehyde chloride ligand was prepared from 5-chloromethyl salicylaldehyde [24] and triethylamine in THF. The products were characterized by elemental analysis, UV and NMR spectroscopy, as reported [22].…”

Section: Methodsmentioning

confidence: 99%

Fluorescence emission and enhanced photochemical stability of ZnII-5-triethyl ammonium methyl salicylidene ortho-phenylendiiminate interacting with native DNA

Barone

Ruggirello

Silvestri

et al. 2010

Journal of Inorganic Biochemistry

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Section: Methodsmentioning

confidence: 99%

Fluorescence emission and enhanced photochemical stability of ZnII-5-triethyl ammonium methyl salicylidene ortho-phenylendiiminate interacting with native DNA

Barone

Ruggirello

Silvestri

et al. 2010

Journal of Inorganic Biochemistry

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“…1) were synthesized [21] by the reaction of 5-(triethylammoniummethyl)salicylaldehyde chloride, 1,2 phenylendiamine and copper(II) or zinc(II) acetate in a 2:1.1:1 molar ratio, in doubly distilled water, and isolated as perchlorate salts. The 5-(triethylammoniummethyl) salicylaldeide chloride ligand was prepared from 5-chloromethyl salicylaldeide [28] and triethylamine in THF. The products were characterized by elemental analysis, UV spectroscopy, and/or 1 H NMR and 13 The NMR spectra were recorded on a Bruker Avance 300 spectrometer.…”

Section: Methodsmentioning

confidence: 99%

The interaction of native DNA with Zn(II) and Cu(II) complexes of 5-triethyl ammonium methyl salicylidene orto-phenylendiimine

Silvestri

Barone

Ruisi

et al. 2007

Journal of Inorganic Biochemistry

106

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The interaction of native calf thymus DNA with the Zn(II) and Cu(II) complexes of 5-triethyl ammonium methyl salicylidene ortophenylendiimine (ZnL 2+ and CuL 2+ ), in 1 mM Tris-HCl aqueous solutions at neutral pH, has been monitored as a function of the metal complex-DNA molar ratio by UV absorption spectrophotometry, circular dichroism (CD) and fluorescence spectroscopy. The results support for an intercalative interaction of both ZnL 2+ and CuL 2+ with DNA, showing CuL 2+ an affinity of approximately 10 times higher than ZnL 2+ . In particular, the values of the binding constant, determined by UV spectrophotometric titration, equal to 7.3 · 10 4 and 1.3 · 10 6 M À1 , for ZnL 2+ and CuL 2+ , respectively, indicate the occurrence of a marked interaction with a binding size of about 0.7 in base pairs. The temperature dependence of the absorbance at 258 nm suggests that both complexes strongly increase the DNA melting temperature (Tm) already at metal complex-DNA molar ratios equal to 0.1. As evidenced by the quenching of the fluorescence of ethidium bromide-DNA solutions in the presence of increasing amounts of metal complex, ZnL 2+ and CuL 2+ are able to displace the ethidium cation intercalated into DNA. A tight ZnL 2+ -DNA and CuL 2+ -DNA binding has been also proven by the appearance, in both metal complex-DNA solutions, of a broad induced CD band in the range 350-450 nm. In the case of the CuL 2+ -DNA system, the shape of the CD spectrum, at high CuL 2+ content, is similar to that observed for w-DNA solutions. Such result allowed us to hypothesize that CuL 2+ induces the formation of supramolecular aggregates of DNA in aqueous solutions.

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“…[33,36] The substituted salicylaldehydes used in the syntheses were prepared by literature procedures. [41] Solvents for catalytic cyclopropanation were purified according to standard procedures. [42] cis-β-Methylstyrene was prepared by hydrogenation of 1-phenyl-1-propyne (Aldrich) using Lindlar catalysts.…”

Section: Methodsmentioning

confidence: 99%

Copper Complexes of Chiral Tetradentate Binaphthyl Schiff-Base Ligands: Syntheses, X-ray Crystal Structures and Activity in Catalytic Asymmetric Cyclopropanation of Alkenes

Che

Kwong

Chu

et al. 2002

Eur. J. Inorg. Chem.

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441. The Sommelet reaction. Part III. The choice of solvent and the effect of substituents

Cited by 63 publications

References 0 publications

Fluorescence emission and enhanced photochemical stability of ZnII-5-triethyl ammonium methyl salicylidene ortho-phenylendiiminate interacting with native DNA

Fluorescence emission and enhanced photochemical stability of ZnII-5-triethyl ammonium methyl salicylidene ortho-phenylendiiminate interacting with native DNA

The interaction of native DNA with Zn(II) and Cu(II) complexes of 5-triethyl ammonium methyl salicylidene orto-phenylendiimine

Copper Complexes of Chiral Tetradentate Binaphthyl Schiff-Base Ligands: Syntheses, X-ray Crystal Structures and Activity in Catalytic Asymmetric Cyclopropanation of Alkenes

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