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Basir, Ghazala; Lam, Tina Poy Wing; Wai‐Sum, O; Ho, Pak Chung

doi:10.1023/a:1009489518468

Cited by 3 publications

(1 citation statement)

References 15 publications

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“…After stratifying the studies according to the previously identified age bands, a mean ovarian PI of 1.49 [1.38–1.60], 2.69 [2.03–3.35], 1.57 [0.46–2.67], 0.80 [0.65–0.95], and 2.96 [2.66–3.26] was found in the 1st (< 20 years; n = 1 study) [ 57 b], 2nd (≥ 20 and < 25 years; n = 5 studies) [ 24 , 36 , 76 , 77 , 82 ], 3rd (≥ 25 and < 30 years; n = 3 studies) [ 3 , 37 , 101 ], 4th (≥ 30 and < 35 years; n = 4 studies) [ 33 , 46 , 70 , 93 ], and 5th groups (≥ 35 years; n = 1 study) [ 83 ], respectively, with a statistically significant difference between the five groups ( Q = 187.57, p < 0.0001) (Fig. 5 ).…”

Section: Resultsmentioning

confidence: 99%

The physiological sonographic features of the ovary in healthy subjects: a joint systematic review and meta-analysis by the Italian Society of Gynecology and Obstetrics (SIGO) and the Italian Society of Endocrinology (SIE)

Moro

Scavello²,

Maseroli³

et al. 2022

J Endocrinol Invest

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Purpose There is a lack of uniformity in the definition of normal ovary ultrasound parameters. Our aim was to summarize and meta-analyze the evidence on the topic. Full-text English articles published through December 31, 2020 were retrieved via MEDLINE and Embase. Data available for meta-analysis included: ovarian follicular count, ovarian volume, and ovarian Pulsatility Index (PI) assessed by Doppler ultrasound. Methods Cohort, cross-sectional, prospective studies with a single or double arm were considered eligible. Interventional studies were included when providing baseline data. Both studies on pre- and post-menopausal women were screened; however, data on menopausal women were not sufficient to perform a meta-analysis. Studies on pre-pubertal girls were considered separately. Eighty-one papers were included in the meta-analysis. Results The mean ovarian volume was 6.11 [5.81–6.42] ml in healthy women in reproductive age (5.81–6.42) and 1.67 ml [1.02–2.32] in pre-pubertal girls. In reproductive age, the mean follicular count was 8.04 [7.26–8.82] when calculated in the whole ovary and 5.88 [5.20–6.56] in an ovarian section, and the mean ovarian PI was 1.86 [1.35–2.37]. Age and the frequency of the transducers partly modulated these values. In particular, the 25–30-year group showed the higher mean follicular count (9.27 [7.71–10.82]), followed by a progressive age-related reduction (5.67 [2.23–9.12] in fertile women > 35 years). A significant difference in follicular count was also found according to the transducer’s upper MHz limit. Conclusion Our findings provide a significant input to improve the interpretation and diagnostic accuracy of ovarian ultrasound parameters in different physiological and pathological settings.

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