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Jacobs, Claudia; Müller, Rainer H.

doi:10.1023/a:1014276917363

Cited by 378 publications

(96 citation statements)

References 4 publications

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“…The zeta potential values of CNC colloids extracted from filter paper (−40.5 ± 2.5 to −43.8 ± 0.8 mV) and wood pulp (−38.9 ± 2.7 to −42.6 ± 3.5 mV) (Table 4) were above the minimum threshold (±30 mV) for electrostatic stability considering their absolute values [54]. Studies have reported zeta potential values of −15 mV from controlled microbial hydrolysis of filter paper [55], −25 to −31 mV from acid hydrolysis of cotton fibers [9], −31 mV from enzymatic treatment of recycled paper [56], and −52 to −58 mV from acid hydrolysis of filter paper [35].…”

Section: Resultsmentioning

confidence: 99%

Characterization of Cellulase-Treated Fibers and Resulting Cellulose Nanocrystals Generated through Acid Hydrolysis

et al. 2018

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Integrating enzymatic treatment and acid hydrolysis potentially improves the economics of cellulose nanocrystal (CNC) production and demonstrates a sustainable cellulosic ethanol co-generation strategy. In this study, the effect of enzymatic treatment on filter paper and wood pulp fibers, and CNCs generated via subsequent acid hydrolysis were assessed. Characterization was performed using a pulp quality monitoring system, scanning and transmission electron microscopies, dynamic light scattering, X-ray diffraction, and thermogravimetric analysis. Enzymatic treatment partially reduced fiber length, but caused swelling, indicating simultaneous fragmentation and layer erosion. Preferential hydrolysis of less ordered cellulose by cellulases slightly improved the crystallinity index of filter paper fiber from 86% to 88%, though no change was observed for wood pulp fibre. All CNC colloids were stable with zeta potential values below −39 mV and hydrodynamic diameters ranging from 205 to 294 nm. Furthermore, the temperature for the peak rate of CNC thermal degradation was generally not affected by enzymatic treatment. These findings demonstrate that CNCs of comparable quality can be produced from an enzymatically-mediated acid hydrolysis biorefining strategy that co-generates fermentable sugars for biofuel production.

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Section: Resultsmentioning

confidence: 99%

Characterization of Cellulase-Treated Fibers and Resulting Cellulose Nanocrystals Generated through Acid Hydrolysis

et al. 2018

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“…As described in our previous report, the nanosuspension of curcumin with various stabilizers (PVA, PVP, Na-CMC, TPGS and SDS) were prepared by using high pressure homogenization (HPH) Micron Lab 40 (APV Deutchland GmbH, Germany) [22]. Both neutral and ionic stabilizers were used to prevent aggregation ( Figure 5).…”

Section: Preparation Of Curcumin Nanosuspensionmentioning

confidence: 99%

Destabilization Mechanism of Ionic Surfactant on Curcumin Nanocrystal against Electrolyte

Rachmawati¹,

Rahma²,

Shaal³

et al. 2016

Preprint

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Abstract:We have successfully developed curcumin nanosuspension aimed for oral delivery. The main purpose is to improve bioavailability through enhancing its solubility. The nanoparticles were stabilized using various stabilizers including polyvinyl pyrrolidone (PVP), polyvinyl alcohol (PVA), sodium carboxymethylcellulose (Na-CMC), d-alpha tocopheryl polyethylene glycol 1000 succinate (TPGS), and sodium dodecyl sulfate (SDS). The average diameter of particles, microscopic appearance, and sedimentation of each preparation was observed and compared. Each stabilizer demonstrated different degree of inhibition of particle aggregation under electrolyte-containing simulated gastrointestinal (GIT) fluid. Non-ionic stabilizers (PVA, PVP, and TPGS) has shown to preserve the nanosuspension stability against electrolytes. In contrast, strong ionic surfactants such as SDS were found to be very sensitive to electrolytes. The results can provide useful information for the formulators to choose the most suitable stabilizers by considering the nature of stabilizers and physiological characteristics of target site of the drug.

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“…It is generally acknowledged that a zeta potential of approximately ± 30 mV is required as minimum. In a combined steric stabilization (HPMC, PVP) and electrostatic (lecithin, poloxamer 188), as a rough guide line ± 20 mV are sufficient [4]. …”

Section: Particle Size and Zeta Potential Analysismentioning

confidence: 99%

“…Nanosuspensions for drug delivery have gained much interest as way to address solubility problems [4]. Nanosuspension of drug is a sub-micron colloidal dispersion of pure particles of the drug, which is stabilized by surfactants [5].…”

Section: Introductionmentioning

confidence: 99%

Development and in vitro evaluation of deacety mycoepoxydiene nanosuspension

Wang¹,

Liu²,

Zhang³

et al. 2011

Colloids and Surfaces B: Biointerfaces

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Abstract: High-pressure homogenization is a production method to obtain nanosuspensions with budesonide for pulmonary applica-

Cited by 378 publications

References 4 publications

Characterization of Cellulase-Treated Fibers and Resulting Cellulose Nanocrystals Generated through Acid Hydrolysis

Characterization of Cellulase-Treated Fibers and Resulting Cellulose Nanocrystals Generated through Acid Hydrolysis

Destabilization Mechanism of Ionic Surfactant on Curcumin Nanocrystal against Electrolyte

Development and in vitro evaluation of deacety mycoepoxydiene nanosuspension

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