4-Styrylpyrimidines as a new class of cytokinins.

Cytokinin Activity of 4-Aminopyridopyrimidines toward the Growth of Tobacco Callus

“…Syntheses of the following compounds were conducted as reported: 1,7) 2,7) 4,8) 5,8) 6,8) 7,6) S,6) 9,6) 10,6) 11,10) 12,7) 13,7) 15,7) and 16. 7 ) 2-Methyl-4-anilinopyrido [3,. A mixture of 2-methyl-4-chloropyrido[3,2-d]pyrimidine 7) (33 mg, 0.18 mmol) and aniline (102 mg, 1.1 mmol) in methanol (20ml) was stirred at room temperature for a few minutes.…”

“…The development of synthetic cytokinins has revealed that intact purine nucleus is not necessary for cytokinin activity; some azaand deazapurines have shown strong activity in a tobacco callus assay.1) Additionally, derivatives of simple azaheterocycles such as 4-pyridylureas 2 ) and 4-styrylpyrimidines 3 ) are also strongly cytokinin-active. However, there have been few studies on cytokinin analogs of azanaphthalenes,4,5) and particularly pyridopyrimidines.…”