(4-Bromophenyl)(1-phenylsulfonyl-1H-indol-2-yl)methanone

Abstract

In the title compound, C21H14BrNO3S, the indole ring system forms dihedral angles of 65.64 (8) and 59.30 (8)°, respectively, with the phenyl and bromo­phenyl rings. In the crystal, mol­ecules are connected by a C—H⋯O hydrogen bond, forming a chain along [101]. The chains are further connected by weak inter­molecular C—H⋯π inter­actions, forming a layer parallel to the ac plane.

Ethyl 1-phenylsulfonyl-1H-indole-2-carboxylate

“…The geometric parameters of the title molecule ( Fig. 1) agree well with reported similar structures (Chakkaravarthi et al, 2010) The dihedral angle between the six membered ring of the indole moiety and the benzene ring is 72.40 5…”

“…For the biological activity of Indole derivatives, see: Joshi & Chand (1982); Pomarnacka & Kozlarska-Kedra (2003); For a related structure, see: Chakkaravarthi et al (2010). Table 1 Hydrogen-bond geometry (Å , ).…”

(E)-1-[2-(4-Fluoro-2-nitrostyryl)-1-phenylsulfonyl-1H-indol-3-yl]propan-1-one

“…The geometric parameters of (I) (Fig. 1) are agree well with the reported structures (Chakkaravarthi et al, 2008;2010).…”

“…For related structures, see: Chakkaravarthi et al (2008Chakkaravarthi et al ( , 2010. For details of the configuration at the S atom, see: Bassindale (1984).…”

Conformational Variability in Sulfonamide Chalcone Hybrids: Crystal Structure and Cytotoxicity

“…In sequence, crystal structure of two TSAHC analogs, which cytotoxicity is reported here (compounds 5 and 6), 26 were elucidated by our research group. Not so much similar to TSAHC and its analogs, all of them owing arylsulfonamide moiety attached in the 1-phenyl group from chalcone scaffold in the para-position, crystal structure of some other related compound with arylsulfonamide bonded in the ortho-position of either 1-phenyl (two compounds) 27,28 or 3-phenyl (six compounds) [29][30][31][32][33][34] ring from chalcone core has been also determined.…”