“…Numerous methods have been proposed for automatic segmentation of vasculature and their taxonomy is given in Suri et al (2002). They are based on various principles, including expectation maximization (Wilson and Noble, 1999), region growing (Chapman et al, 2004), fuzzy connectedness (Forkert et al, 2009), skeletonization (Yim et al, 2000), active contours (Yu et al, 2008), level set for CTA (Manniesing et al, 2006) and for MRA (Farag et al, 2004), mathematical morphology (Zana and Klein, 2001), and atlas-related (Passat et al, 2005). These methods usually produce incomplete segmentations with numerous false positives.…”