3D Turbo Spin-Echo Sequence with Motion-Sensitized Driven-Equilibrium Preparation for Detection of Brain Metastases on 3T MR Imaging

Abstract

BACKGROUND AND PURPOSE: MSDE preparation is a technique for black-blood imaging. Our purpose was to evaluate the usefulness of a 3D TSE sequence with MSDE preparation in detecting brain metastases by comparing it with conventional sequences.

Detection of Brain Metastases by 3-Dimensional Magnetic Resonance Imaging at 3 T

“…3 and 4). Previous studies have reported increases in false positive findings with T1-weighted 3D-FSE imaging, due to the residual signal from the blood vessels (11,28). In this study, six enhanced vessels were rated as probable or definite metastases.…”

“…However, depending on the velocity encoding (VENC) setting, suppression of signal from the blood vessels of the brain surface may not be complete. Some vessels with very slow flow may remain partially hyperintense at the lowest possible VENC setting (28). Partial hyperintensity of the blood vessels can mimic brain metastases, especially when continuity is lost and the normal tubular appearance cannot be identified  which may lead to increase in false positive findings.…”

“…According to Nagao et al, the contrastenhanced T1-FSE sequence in combination with the contrast-enhanced T1-GRE sequence provide improved accuracy than either sequence alone (28). In this study, altogether three MR imaging sequences  T1-VISTA, 3D-T2-FLAIR, and 3D-T1-FLAIR imaging ─ were acquired.…”

3D turbo field echo with diffusion-sensitized driven-equilibrium preparation technique (DSDE-TFE) versus echo planar imaging in evaluation of diffusivity of retinoblastoma

“…19,20 MSDE preparations have also been applied to brain imaging for the detection of metastatic tumours. 21 Compared with an MSDE preparation, the DSDE-prepared sequence has stronger motion-sensitizing gradients, which enables diffusion-weighting in the anteroposterior direction. The DSDE preparation was originally developed to reduce image distortion in the imaging of peripheral nerves, 17 and it was then optimized for orbital imaging in the present study.…”

“…22,23 For the DSDE-TFE, motion-probing gradients were used in one direction with b-values of 0 and 500 s mm 22 Axial T 1 weighted images, T 2 weighted images with fat suppression and post-contrast T 1 weighted images with fat suppression were also obtained. The contrast material was injected at 0.1 mmol kg 21 [gadopentetate dimeglumine (Magnevist®; Bayer, Osaka, Japan), gadodiamide (Omniscan; Daiichi Sankyo, Tokyo, Japan) or gadoteridol (Prohance®; Eisai, Tokyo, Japan)].…”